Radiation-Free Heart Catheterization Using MRI

Participants undergo general anesthesia, and vascular access is obtained in the x-ray
catheterization lab. Next the participant is transferred into the MRI scanner where a focused
MRI examination is performed. Catheters are then guided into the heart chambers using
real-time MRI guidance to perform conventional cardiac catheterization steps. If time allows,
additional research MRI is performed before the participant is returned to the x-ray
catheterization lab. If any MRI guided catheterization steps are unsuccessful, the clinically
indicated step is performed after the participant returns to the x-ray catheterization lab
using conventional x-ray guided pictures.

Inclusion Criteria:

- Undergoing a medically necessary cardiovascular catheterization

Exclusion Criteria:

- Cardiovascular instability including hemodynamic instability (such as requiring
significant vasoactive infusion support) or mechanical hemodynamic support.

- Women who are pregnant

- Women who are nursing and who do not plan to discard breast milk for 24 hours

- Patients with a contraindication to MRI scanning will be excluded. These
contraindications include patients with the following devices:

1. Central nervous system aneurysm clips

2. Implanted neural stimulator

3. Implanted cardiac pacemaker or defibrillator which are not MR safe or MR
conditional according to the manufacturer

4. Cochlear implant

5. Ocular foreign body (e.g. metal shavings)

6. Implanted Insulin pump

7. Metal shrapnel or bullet

Exclusion criteria for Gadolinium (contrast agent)

1. Renal disease with estimated glomerular filtration rate < 30 ml/min/1.73 m2 body surface
area