Early Versus Late Voiding Trials After Prolapse Repair



Status:Terminated
Conditions:Overactive Bladder, Women's Studies, Urology
Therapuetic Areas:Gastroenterology, Nephrology / Urology, Reproductive
Healthy:No
Age Range:21 - Any
Updated:6/29/2018
Start Date:February 2016
End Date:March 1, 2017

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Normal Voiding Function After Surgical Repair of Pelvic Organ Prolapse: A Randomized Trial Comparing Day of Surgery Retrograde Void Trials to Standard Postoperative Day One Retrograde Void Trials

The primary aim of this study is to determine if normal bladder function (the ability to
empty the bladder during spontaneous urination) after surgical repair of pelvic organ
prolapse returns faster in patients who have a retrograde voiding trial the day of surgery
versus patients who have a retrograde voiding trial on postoperative day one. Half of
participants will have a voiding trial 4 hours after surgery, while the other half will have
the voiding trial postoperative day one.

Overnight indwelling catheterization is a prevalent practice after surgical repair of pelvic
organ prolapse. A voiding trial is performed postoperative day one to determine if urinary
retention or abnormal bladder function exists. A significant number of patients ranging from
26-47% will require continued catheterization post-op for urinary retention in order to avoid
injuries associated with over distention of the bladder and ureteral reflux.

This study aims to explore a strategy to reduce the length of catheterization
post-operatively by testing the bladder at a closer interval to surgery. An earlier voiding
trial may improve patient perioperative satisfaction and decrease catheter associated urinary
tract infections. Additional benefits that may also be seen are earlier first ambulation and
quicker achievement of post-op discharge milestones (pain control, ambulation with symptoms,
oral intake tolerance and completion of a voiding trial). To date, few studies have attempted
a day of surgery voiding trial in patients being admitted for repair of pelvic organ prolapse
that requires an overnight admission.

Inclusion Criteria:

- surgical management of pelvic organ prolapse requiring an overnight hospital admission

Exclusion Criteria:

- same day surgery

- non-ambulatory (allowed to use an assistive device)

- inability to provide informed consent, age < 21 years

- pregnancy or desire for future pregnancy

- systematic disease known to affect bladder function (Parkinson's disease, Multiple
Sclerosis, Spina Bifida, spinal cord injury or trauma and neurogenic bladder)

- known preoperative urinary retention (defined as a post-void residual > 100mL)

- an untreated urinary tract infection at the time of surgery

- treatment at the time of surgery for urinary tract infection

- symptoms of urinary tract infection on the day of surgery
We found this trial at
1
site
300 Halket St.
Pittsburgh, Pennsylvania 15213
1-866-MyMagee (696-2433)
Phone: 412-641-5388
Magee-Womens Hospital of UPMC Magee-Womens Hospital of UPMC is a world-class center for both women's...
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mi
from
Pittsburgh, PA
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