Epidemiology of H. Pylori Transmission



Status:Completed
Conditions:Infectious Disease
Therapuetic Areas:Immunology / Infectious Diseases
Healthy:No
Age Range:18 - 55
Updated:4/21/2016
Start Date:June 2008
End Date:July 2013

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Epidemiology of H. Pylori Transmission and Immunoepidemiology of Concomitant Infections

This observational epidemiologic study with nested cross-sectional and longitudinal aims
will evaluate host immune response to mixed chronic infections (Helicobacter pylori, latent
tuberculosis, intestinal helminthiasis) in recent US immigrants.

1750 clinically-well, adult (age 18-55 years), recent immigrants (<2 years U.S. residence),
referred through cooperating public health clinics in the Santa Clara Valley area, CA will
be screened for H. pylori, helminth, and latent tuberculosis infections ["Screening"
population]. Of these 1750, 426 will be selected for more intensive study (Cohort
population), 105 of whom will receive baseline endoscopy. Of those selected for the cohort,
300 are expected to complete a 9-month follow-up assessment, 75 of whom are expected to
undergo a second follow-up endoscopy.

Inclusion Criteria:

- Between 18-55 years of age

- Either sex

- If female not pregnant or breastfeeding

- Lived in the United States less than 2 years

- Healthy

- Scheduled for Tuberculosis Skin Test (TST)

Exclusion Criteria:

- Under 18 and older than 55 years of age,

- Pregnant or breastfeeding

- Have lived in Unites States more that 2 years

- Chronic illness

- Not planning to get a TST
We found this trial at
2
sites
291 Campus Dr
Stanford, California 94305
(650) 725-3900
Stanford University School of Medicine Vast in both its physical scale and its impact on...
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Stanford, CA
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San Jose, California 95122
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San Jose, CA
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