Epidemiology of H. Pylori Transmission
| Status: | Completed |
|---|---|
| Conditions: | Infectious Disease |
| Therapuetic Areas: | Immunology / Infectious Diseases |
| Healthy: | No |
| Age Range: | 18 - 55 |
| Updated: | 4/21/2016 |
| Start Date: | June 2008 |
| End Date: | July 2013 |
Epidemiology of H. Pylori Transmission and Immunoepidemiology of Concomitant Infections
This observational epidemiologic study with nested cross-sectional and longitudinal aims
will evaluate host immune response to mixed chronic infections (Helicobacter pylori, latent
tuberculosis, intestinal helminthiasis) in recent US immigrants.
will evaluate host immune response to mixed chronic infections (Helicobacter pylori, latent
tuberculosis, intestinal helminthiasis) in recent US immigrants.
1750 clinically-well, adult (age 18-55 years), recent immigrants (<2 years U.S. residence),
referred through cooperating public health clinics in the Santa Clara Valley area, CA will
be screened for H. pylori, helminth, and latent tuberculosis infections ["Screening"
population]. Of these 1750, 426 will be selected for more intensive study (Cohort
population), 105 of whom will receive baseline endoscopy. Of those selected for the cohort,
300 are expected to complete a 9-month follow-up assessment, 75 of whom are expected to
undergo a second follow-up endoscopy.
referred through cooperating public health clinics in the Santa Clara Valley area, CA will
be screened for H. pylori, helminth, and latent tuberculosis infections ["Screening"
population]. Of these 1750, 426 will be selected for more intensive study (Cohort
population), 105 of whom will receive baseline endoscopy. Of those selected for the cohort,
300 are expected to complete a 9-month follow-up assessment, 75 of whom are expected to
undergo a second follow-up endoscopy.
Inclusion Criteria:
- Between 18-55 years of age
- Either sex
- If female not pregnant or breastfeeding
- Lived in the United States less than 2 years
- Healthy
- Scheduled for Tuberculosis Skin Test (TST)
Exclusion Criteria:
- Under 18 and older than 55 years of age,
- Pregnant or breastfeeding
- Have lived in Unites States more that 2 years
- Chronic illness
- Not planning to get a TST
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