Examining the Link Between Trace Elements and Cardiovascular Disease Risk Factors in Young Adults
| Status: | Completed |
|---|---|
| Conditions: | High Blood Pressure (Hypertension), Peripheral Vascular Disease, Cardiology, Endocrine |
| Therapuetic Areas: | Cardiology / Vascular Diseases, Endocrinology |
| Healthy: | No |
| Age Range: | 20 - 32 |
| Updated: | 4/21/2016 |
| Start Date: | May 2006 |
| End Date: | April 2011 |
Trace Elements and CVD Risk Factors Among Young Adults
Cardiovascular disease (CVD) affects millions of people in the United States; each year,
more people die from CVD than from any other disease. There are many dietary and lifestyle
factors that may increase the risk of developing CVD. Preliminary research has shown that
the presence of certain trace elements may be associated with the development of CVD. This
study will examine toenail clippings and laboratory data to evaluate the link between trace
elements and CVD risk factors in young adults.
more people die from CVD than from any other disease. There are many dietary and lifestyle
factors that may increase the risk of developing CVD. Preliminary research has shown that
the presence of certain trace elements may be associated with the development of CVD. This
study will examine toenail clippings and laboratory data to evaluate the link between trace
elements and CVD risk factors in young adults.
CVD is a disorder that affects the heart's ability to function normally. The most common
cause of heart disease is narrowing or blockage of the coronary arteries, which supply blood
to the heart. There are many risk factors for CVD, including inflammation, high blood
pressure, high cholesterol, and obesity. Small quantities of trace elements, also known as
micronutrients, are essential in maintaining a healthy body. Research has shown that some
trace elements may be associated with the development of CVD, but more research is needed to
confirm this connection. This study will examine concentrations of several trace elements in
toenail samples of young adults participating in the Coronary Artery Risk Development in
Young Adults (CARDIA) study. The CARDIA study is measuring changes in CVD risk factors in
individuals as they age and is identifying lifestyle habits that influence those changes.
The purpose of this study is to determine the link between trace elements and CVD risk
factors in young adults. The results of this study may help to identify whether dietary,
lifestyle, or environmental factors can be modified at a young age to prevent the
development of CVD.
This study will examine laboratory and medical history data of participants who are already
enrolled in the CARDIA study; there are no additional study visits specifically for this
study. Toenail samples collected from participants during their Year 2 CARDIA study visit in
the late 1980's will be examined to determine the presence of selenium, chromium, arsenic,
and mercury. Participants' CARDIA study data will be reviewed and several CVD risk factors
will be analyzed, including the thickness of heart arteries; calcium buildup within the
arteries; inflammatory markers, such as high sensitivity C-reactive protein and interleukin
6; blood pressure levels; body weight; and levels of cholesterol, fat, and sugar.
cause of heart disease is narrowing or blockage of the coronary arteries, which supply blood
to the heart. There are many risk factors for CVD, including inflammation, high blood
pressure, high cholesterol, and obesity. Small quantities of trace elements, also known as
micronutrients, are essential in maintaining a healthy body. Research has shown that some
trace elements may be associated with the development of CVD, but more research is needed to
confirm this connection. This study will examine concentrations of several trace elements in
toenail samples of young adults participating in the Coronary Artery Risk Development in
Young Adults (CARDIA) study. The CARDIA study is measuring changes in CVD risk factors in
individuals as they age and is identifying lifestyle habits that influence those changes.
The purpose of this study is to determine the link between trace elements and CVD risk
factors in young adults. The results of this study may help to identify whether dietary,
lifestyle, or environmental factors can be modified at a young age to prevent the
development of CVD.
This study will examine laboratory and medical history data of participants who are already
enrolled in the CARDIA study; there are no additional study visits specifically for this
study. Toenail samples collected from participants during their Year 2 CARDIA study visit in
the late 1980's will be examined to determine the presence of selenium, chromium, arsenic,
and mercury. Participants' CARDIA study data will be reviewed and several CVD risk factors
will be analyzed, including the thickness of heart arteries; calcium buildup within the
arteries; inflammatory markers, such as high sensitivity C-reactive protein and interleukin
6; blood pressure levels; body weight; and levels of cholesterol, fat, and sugar.
Inclusion Criteria:
- Enrolled in the CARDIA study; this current study will be using existing CARDIA study
data and will not be recruiting any new participants
We found this trial at
1
site
University of North Carolina at Chapel Hill Carolina’s vibrant people and programs attest to the...
Click here to add this to my saved trials
