Screening for Gynecologic Cancers in Hereditary Nonpolyposis Colorectal Cancer (HNPCC) Patients



Status:Completed
Conditions:Colorectal Cancer, Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:25 - Any
Updated:4/21/2016
Start Date:May 2003
End Date:March 2016

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Screening for Gynecologic Cancers Among Women With Hereditary Non-Polyposis Colon Cancer (HNPCC)

Among women with HNPCC, this study will assess:

1. Knowledge of screening recommendations for endometrial and ovarian cancers.

2. Perceived risk and cancer worries regarding endometrial, ovarian and colorectal
cancers.

3. Adherence to screening recommendations for endometrial, ovarian and colon cancers.

4. Perceived benefits,supports and barriers to endometrial and ovarian cancer screening.

5. Patterns of communication about endometrial and ovarian cancer risk within families
with HNPCC and with health care providers.

6. Patient preferences for potential cancer screening and cancer prevention strategies
related to HNPCC-associated cancers.

Women who are at risk for HNPCC will be recruited to participate in this pilot study.

Women will be invited to participate in the study either through a mailed invitation or
during a visit to M.D. Anderson for clinical services or for research purposes.

Women who wish to participate in the study will complete an informed consent, and will
subsequently schedule an appointment with a research coordinator to complete the study
questionnaire by telephone.

Inclusion Criteria:

1. Being female

2. Being 25 years of age or older

3. Having an HNPCC-predisposing mutation and/or having a family history of cancer that
meets the Amsterdam or Amsterdam II criteria for HNPCC

Exclusion Criteria:

1. Persons who have tested negative for a known HNPCC-predisposing mutation in their
family

2. Persons who have no family HNPCC mutation and have not met the Amsterdam I/II
criteria

3. Being younger than 25 years old

4. Note: Women who have had a prior history of colorectal cancer or polyps will not be
excluded unless they meet one of the above exclusion criteria.
We found this trial at
1
site
1515 Holcombe Blvd
Houston, Texas 77030
 713-792-2121
University of Texas M.D. Anderson Cancer Center The mission of The University of Texas MD...
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from
Houston, TX
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