E-cigarettes and Blood Vessel Function
| Status: | Recruiting |
|---|---|
| Conditions: | Smoking Cessation, Tobacco Consumers |
| Therapuetic Areas: | Pulmonary / Respiratory Diseases |
| Healthy: | No |
| Age Range: | 21 - 45 |
| Updated: | 1/26/2019 |
| Start Date: | August 2015 |
| End Date: | December 2022 |
| Contact: | Holly R Middlekauff, MD |
| Email: | hmiddlekauff@mednet.ucla.edu |
| Phone: | 310-206-6672 |
The Effects of Electronic Cigarettes on Endothelial Function and Oxidative Stress
Randomized controlled trial of electronic cigarettes with nicotine, without nicotine, and
sham control, on endothelial function and markers of oxidative stress.
sham control, on endothelial function and markers of oxidative stress.
Participants will use an electronic cigarette on 3 occasions: 1) with nicotine, 2) without
nicotine, 3) sham control, and undergo a measure of endothelial function called brachial
artery flow mediated dilatation (FMD). Additionally, oxidative stress will be measured pre
and post exposure.
nicotine, 3) sham control, and undergo a measure of endothelial function called brachial
artery flow mediated dilatation (FMD). Additionally, oxidative stress will be measured pre
and post exposure.
Inclusion Criteria:
- Healthy
Exclusion Criteria:
- Cardiac disease
- Respiratory disease
- Diabetes mellitus
We found this trial at
1
site
Los Angeles, California 90095
Principal Investigator: Holly R Middlekauff, MD
Phone: 310-206-6672
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