Sparsity-based Magnetic Resonance Imaging of Cardiac Arrhythmias

In the proposed research, investigators will extend conventional cardiac magnetic resonance
methods to enable the creation of high-quality cine CMR images in the presence of multiple
kinds of arrhythmia. Two arrhythmia-tolerant imaging methods will be adopted, which are
particularly useful in arrhythmia: 1) 3D imaging, which is useful for many purposes,
including "road mapping" of electrophysiology (EP) procedures, and 2) late gadolinium
enhancement (LGE), which is useful for delineating abnormal myocardium, including fibrotic
regions that can serve as sources of arrhythmias.

Inclusion Criteria for Arrhythmia Patients:

- Patients diagnosed with heart arrhythmia scheduled for routine clinical MRI
examinations).

- Patients scheduled for routine clinical MRI examinations who do not have a specific
known diagnosis of arrhythmia, but who may be found to have image degradation due to
arrhythmia during the CMR examination.

Inclusion Criteria for Controls:

- No history of heart arrhythmia.

Exclusion Criteria for Patients and Controls:

- Hemodynamic instability.

- Contraindications for MRI examinations (e.g., pacemakers or ferromagnetic vascular
clips).

- History of prior cardiovascular disease or significant risk factors:

- Diabetes, hypertension, smoking, and hyperlipidemia, etc.