Long-Term Safety of Lampalizumab Intravitreal (ITV) Injections in Participants With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (OMASPECT)



Status:Terminated
Conditions:Ocular
Therapuetic Areas:Ophthalmology
Healthy:No
Age Range:Any
Updated:3/8/2019
Start Date:July 21, 2016
End Date:January 31, 2018

Use our guide to learn which trials are right for you!

A Multicenter, Open-Label Extension Study to Evaluate the Long-Term Safety and Tolerability of Lampalizumab in Patients With Geographic Atrophy Secondary to Age-Related Macular Degeneration Who Have Completed a Roche-Sponsored Study

This multicenter open-label extension study is designed to evaluate the safety and
tolerability of lampalizumab intravitreal injections in participants with GA secondary to
age-related macular degeneration (AMD) who completed 96 weeks of treatment in Studies GX29176
(NCT02247479) or GX29185 (NCT02247531). The extension will enroll participants from the
parent studies who received investigational lampalizumab, as well as lampalizumab-naive
participants exposed to sham comparator. All participants will receive open-label
lampalizumab in the present study.


Inclusion Criteria:

- Previous enrollment in Studies GX29176 (NCT02247479) or GX29185 (NCT02247531) with
completion of treatment and the Week 96 visit

- Agreement to remain abstinent or use a reliable form of contraception among all men
and among women of child-bearing potential

Exclusion Criteria:

- Concurrent ocular conditions that contraindicate use of lampalizumab or might affect
interpretation of study results or that might increase the risk of treatment
complications

- Concurrent disease, metabolic dysfunction, or physical or laboratory finding that
contraindicates use of lampalizumab or might affect interpretation of study results or
that might increase the risk of treatment complications

- Increased risk of infection

- Pregnancy or lactation
We found this trial at
123
sites
McAllen, Texas 78503
1895
mi
from 02139
McAllen, TX
Click here to add this to my saved trials
4202 E Fowler Ave
Tampa, Florida 33620
(813) 974-2011
University of South Florida The University of South Florida is a high-impact, global research university...
1174
mi
from 02139
Tampa, FL
Click here to add this to my saved trials
98-1079 Moanalua Road
'Aiea, Hawaii 96701
5079
mi
from 02139
'Aiea, HI
Click here to add this to my saved trials
5441 Health Center Drive
Abilene, Texas 79606
1707
mi
from 02139
Abilene, TX
Click here to add this to my saved trials
1220 New Scotland Road
Albany, New York 12208
141
mi
from 02139
Albany, NY
Click here to add this to my saved trials
669 Dean Street
Albury, New South Wales 2640
10373
mi
from 02139
Albury,
Click here to add this to my saved trials
Ann Arbor, Michigan 48105
644
mi
from 02139
Ann Arbor, MI
Click here to add this to my saved trials
Arlington, Texas 76012
1564
mi
from 02139
Arlington, TX
Click here to add this to my saved trials
21 Medical Park Drive
Asheville, North Carolina 28803
771
mi
from 02139
Asheville, NC
Click here to add this to my saved trials
2596
mi
from 02139
Ashland, OR
Click here to add this to my saved trials
Augusta, Georgia 30909
851
mi
from 02139
Augusta, GA
Click here to add this to my saved trials
Aurora, Colorado 80045
1760
mi
from 02139
Aurora, CO
Click here to add this to my saved trials
Austin, Texas 78705
1690
mi
from 02139
Austin, TX
Click here to add this to my saved trials
Austin, Texas 78705
1690
mi
from 02139
Austin, TX
Click here to add this to my saved trials
Bakersfield, California 93309
2590
mi
from 02139
Bakersfield, CA
Click here to add this to my saved trials
Baltimore, Maryland 21209
356
mi
from 02139
Baltimore, MD
Click here to add this to my saved trials
Baltimore, Maryland
357
mi
from 02139
Baltimore, MD
Click here to add this to my saved trials
Bellevue, Washington 98004
2477
mi
from 02139
Bellevue, WA
Click here to add this to my saved trials
Beverly Hills, California 90211
2595
mi
from 02139
Beverly Hills, CA
Click here to add this to my saved trials
1720 7th Avenue South
Birmingham, Alabama 35233
1049
mi
from 02139
Birmingham, AL
Click here to add this to my saved trials
Bloomfield, New Jersey 07003
192
mi
from 02139
Bloomfield, NJ
Click here to add this to my saved trials
800 Washington Street
Boston, Massachusetts 02111
2
mi
from 02139
Boston, MA
Click here to add this to my saved trials
243 Charles Street
Boston, Massachusetts 02114
1
mi
from 02139
Boston, MA
Click here to add this to my saved trials
Boston, Massachusetts 02114
2
mi
from 02139
Boston, MA
Click here to add this to my saved trials
1717 Woolbright Road
Boynton Beach, Florida 33426
1206
mi
from 02139
Boynton Beach, FL
Click here to add this to my saved trials
6035 Fairview Road
Charlotte, North Carolina 28210
722
mi
from 02139
Charlotte, NC
Click here to add this to my saved trials
1300 Jefferson Park Avenue
Charlottesville, Virginia 22903
491
mi
from 02139
Charlottesville, VA
Click here to add this to my saved trials
1606 Gunbarrel Road
Chattanooga, Tennessee 37421
910
mi
from 02139
Chattanooga, TN
Click here to add this to my saved trials
8 Ranoldo Terrace
Cherry Hill, New Jersey 08034
263
mi
from 02139
Cherry Hill, NJ
Click here to add this to my saved trials
Chesterfield, Missouri 63017
1050
mi
from 02139
Chesterfield, MO
Click here to add this to my saved trials
Chevy Chase, Maryland 20815
390
mi
from 02139
Chevy Chase, MD
Click here to add this to my saved trials
Cincinnati, Ohio 45242
735
mi
from 02139
Cincinnati, OH
Click here to add this to my saved trials
Cleveland, Ohio 44122
538
mi
from 02139
Cleveland, OH
Click here to add this to my saved trials
543
mi
from 02139
Cleveland, OH
Click here to add this to my saved trials
2770 North Union Boulevard
Colorado Springs, Colorado 80909
1771
mi
from 02139
Colorado Springs, CO
Click here to add this to my saved trials
640
mi
from 02139
Columbus, OH
Click here to add this to my saved trials
Dallas, Texas 75231
1540
mi
from 02139
Dallas, TX
Click here to add this to my saved trials
Detroit, Michigan 48201
609
mi
from 02139
Detroit, MI
Click here to add this to my saved trials
2351 Erwin Road
Durham, North Carolina 27710
606
mi
from 02139
Durham, NC
Click here to add this to my saved trials
7760 France Avenue South
Edina, Minnesota 55435
1121
mi
from 02139
Edina, MN
Click here to add this to my saved trials
213
mi
from 02139
Edison, NJ
Click here to add this to my saved trials
Florence, South Carolina 29501
733
mi
from 02139
Florence, SC
Click here to add this to my saved trials
Fort Lauderdale, Florida 33334
1229
mi
from 02139
Fort Lauderdale, FL
Click here to add this to my saved trials
Fort Myers, Florida 33907
1250
mi
from 02139
Fort Myers, FL
Click here to add this to my saved trials
Fort Myers, Florida 33912
1252
mi
from 02139
Fort Myers, FL
Click here to add this to my saved trials
Fullerton, California 92835
2577
mi
from 02139
Fullerton, CA
Click here to add this to my saved trials
1432 Kimbrough Road
Germantown, Tennessee 38138
1121
mi
from 02139
Germantown, TN
Click here to add this to my saved trials
Golden, Colorado 80401
1774
mi
from 02139
Golden, CO
Click here to add this to my saved trials
Grand Rapids, Michigan 49525
736
mi
from 02139
Grand Rapids, MI
Click here to add this to my saved trials
200 Motor Parkway
Hauppauge, New York 11788
154
mi
from 02139
Hauppauge, NY
Click here to add this to my saved trials
Houston, Texas 77030
1606
mi
from 02139
Houston, TX
Click here to add this to my saved trials
10300 North Illinois Street
Indianapolis, Indiana 46290
800
mi
from 02139
Indianapolis, IN
Click here to add this to my saved trials
1116 West Ganson Street
Jackson, Michigan 49202
680
mi
from 02139
Jackson, MI
Click here to add this to my saved trials
La Jolla, California 92093
2550
mi
from 02139
La Jolla, CA
Click here to add this to my saved trials
9551 U.S. 78
Ladson, South Carolina 29456
812
mi
from 02139
Ladson, SC
Click here to add this to my saved trials
Las Vegas, Nevada
2367
mi
from 02139
Las Vegas, NV
Click here to add this to my saved trials
4 Princess Road
Lawrenceville, New Jersey 08648
235
mi
from 02139
Lawrenceville, NJ
Click here to add this to my saved trials
16 Hayden Avenue
Lexington, Kentucky 02421
7
mi
from 02139
Lexington, KY
Click here to add this to my saved trials
Lexington, Kentucky 40509
763
mi
from 02139
Lexington, KY
Click here to add this to my saved trials
Los Angeles, California
2588
mi
from 02139
Los Angeles, CA
Click here to add this to my saved trials
360 Merrick Road
Lynbrook, New York 11563
177
mi
from 02139
Lynbrook, NY
Click here to add this to my saved trials
Madison, Wisconsin 53792
(608) 263-2400
University of Wisconsin In achievement and prestige, the University of Wisconsin–Madison has long been recognized...
929
mi
from 02139
Madison, WI
Click here to add this to my saved trials
Marietta, Georgia 30060
931
mi
from 02139
Marietta, GA
Click here to add this to my saved trials
502 East New Haven Avenue
Melbourne, Florida 32901
1121
mi
from 02139
Melbourne, FL
Click here to add this to my saved trials
Monroeville, Pennsylvania 15146
469
mi
from 02139
Monroeville, PA
Click here to add this to my saved trials
Morgantown, West Virginia 26506
497
mi
from 02139
Morgantown, WV
Click here to add this to my saved trials
2485 Hospital Drive
Mountain View, California 94040
2684
mi
from 02139
Mountain View, CA
Click here to add this to my saved trials
3880 Tamiami Trail North
Naples, Florida 34103
1270
mi
from 02139
Naples, FL
Click here to add this to my saved trials
Nashville, Tennessee 37203
940
mi
from 02139
Nashville, TN
Click here to add this to my saved trials
400 Bayonet Street
New London, Connecticut 06320
86
mi
from 02139
New London, CT
Click here to add this to my saved trials
New York, New York
188
mi
from 02139
New York, NY
Click here to add this to my saved trials
460 Park Avenue
New York, New York 10022
185
mi
from 02139
New York, NY
Click here to add this to my saved trials
1500 Tilton Road
Northfield, New Jersey 08225
274
mi
from 02139
Northfield, NJ
Click here to add this to my saved trials
Oakland, California 94609
2680
mi
from 02139
Oakland, CA
Click here to add this to my saved trials
Paducah, Kentucky 42001
996
mi
from 02139
Paducah, KY
Click here to add this to my saved trials
Palm Beach Gardens, Florida 33410
1185
mi
from 02139
Palm Beach Gardens, FL
Click here to add this to my saved trials
Palm Beach Gardens, Florida 33418
1188
mi
from 02139
Palm Beach Gardens, FL
Click here to add this to my saved trials
36949 Cook Street
Palm Desert, California 92211
2500
mi
from 02139
Palm Desert, CA
Click here to add this to my saved trials
2452 Watson Court
Palo Alto, California 94303
2684
mi
from 02139
Palo Alto, CA
Click here to add this to my saved trials
Pensacola, Florida 32503
1214
mi
from 02139
Pensacola, FL
Click here to add this to my saved trials
Philadelphia, Pennsylvania 19107
268
mi
from 02139
Philadelphia, PA
Click here to add this to my saved trials
Phoenix, Arizona 85014
2290
mi
from 02139
Phoenix, AZ
Click here to add this to my saved trials
Phoenix, Arizona 85020
2292
mi
from 02139
Phoenix, AZ
Click here to add this to my saved trials
Plantation, Florida 33324
1235
mi
from 02139
Plantation, FL
Click here to add this to my saved trials
Portland, Maine
99
mi
from 02139
Portland, ME
Click here to add this to my saved trials
Portland, Oregon 97210
2530
mi
from 02139
Portland, OR
Click here to add this to my saved trials
3303 Southwest Bond Avenue
Portland, Oregon 97239
2530
mi
from 02139
Portland, OR
Click here to add this to my saved trials
Poway, California 92064
2561
mi
from 02139
Poway, CA
Click here to add this to my saved trials
Rapid City, South Dakota 57701
1610
mi
from 02139
Rapid City, SD
Click here to add this to my saved trials
Reno, Nevada 89502
2511
mi
from 02139
Reno, NV
Click here to add this to my saved trials
8411 North Run Medical Drive
Richmond, Virginia 23226
466
mi
from 02139
Richmond, VA
Click here to add this to my saved trials
Richmond, Virginia
476
mi
from 02139
Richmond, VA
Click here to add this to my saved trials
160 Sawgrass Drive
Rochester, New York 14620
334
mi
from 02139
Rochester, NY
Click here to add this to my saved trials
Royal Oak, Michigan 48073
615
mi
from 02139
Royal Oak, MI
Click here to add this to my saved trials
Sacramento, California 95817
2621
mi
from 02139
Sacramento, CA
Click here to add this to my saved trials
Sacramento, California 95819
2622
mi
from 02139
Sacramento, CA
Click here to add this to my saved trials
4344 Central Avenue North
Saint Petersburg, Florida 33711
1199
mi
from 02139
Saint Petersburg, FL
Click here to add this to my saved trials
Salt Lake City, Utah
2091
mi
from 02139
Salt Lake City, UT
Click here to add this to my saved trials
1445 Bush Street
San Francisco, California 94107
2690
mi
from 02139
San Francisco, CA
Click here to add this to my saved trials
400 Parnassus Avenue
San Francisco, California 94143
2692
mi
from 02139
San Francisco, CA
Click here to add this to my saved trials
Santa Ana, California 92705
2579
mi
from 02139
Santa Ana, CA
Click here to add this to my saved trials