A Peer-based Mobile-health Intervention to Increase Access & Adherence to Hepatitis C Treatment & HIV Viral Suppression
| Status: | Recruiting |
|---|---|
| Conditions: | HIV / AIDS, Hepatitis, Hepatitis |
| Therapuetic Areas: | Immunology / Infectious Diseases |
| Healthy: | No |
| Age Range: | 18 - 55 |
| Updated: | 8/3/2018 |
| Start Date: | December 19, 2016 |
| End Date: | August 2020 |
| Contact: | Karin E Tobin, PhD |
| Email: | ktobin@jhsph.edu |
| Phone: | 410-502-5368 |
Randomized Controlled Trial of a Social-network Oriented Mobile Health Based Intervention to Increase Access and Adherence to Hepatitis C Treatment and HIV Viral Suppression
The purpose of this study is to test an intervention designed to train persons who inject
drugs (PWID) and are infected with hepatitis C (HCV) and HIV in communication skills to 1)
promote new HCV treatment and care 2) risk reduction and 3) recruit their social network
members for HIV and HCV testing and linkage to care.
drugs (PWID) and are infected with hepatitis C (HCV) and HIV in communication skills to 1)
promote new HCV treatment and care 2) risk reduction and 3) recruit their social network
members for HIV and HCV testing and linkage to care.
The investigators propose recruiting 300 HIV/HCV co-infected PWID (i.e. Index participants).
Half will be randomly assigned to the experimental condition and half to the equal attention
comparison. The experimental intervention will include 8 group sessions that focus on
communication to social network members, medical adherence and risk reduction skills, 2 dyad
sessions with network members, monthly booster sessions for 6 months, and mHealth cuing of
behavior for 6 months. These Index participants will be followed for 24 months (3, 6, 12, 18,
& 24 month assessments). Participants who test positive for HCV will be linked to the Johns
Hopkins Viral Hepatitis clinic to assess liver function and HCV chronicity and if applicable
offered HCV treatment. Additionally, 450 network members will be recruited and will be tested
for HIV and HCV and followed longitudinally to examine the social diffusion and social
network factors associated with adherence among the Index participants.
Half will be randomly assigned to the experimental condition and half to the equal attention
comparison. The experimental intervention will include 8 group sessions that focus on
communication to social network members, medical adherence and risk reduction skills, 2 dyad
sessions with network members, monthly booster sessions for 6 months, and mHealth cuing of
behavior for 6 months. These Index participants will be followed for 24 months (3, 6, 12, 18,
& 24 month assessments). Participants who test positive for HCV will be linked to the Johns
Hopkins Viral Hepatitis clinic to assess liver function and HCV chronicity and if applicable
offered HCV treatment. Additionally, 450 network members will be recruited and will be tested
for HIV and HCV and followed longitudinally to examine the social diffusion and social
network factors associated with adherence among the Index participants.
Inclusion Criteria:
- HCV antibody positive
- HIV antibody positive
- lifetime history of injection drug use
- interrupted HIV care:>3 months since HIV care or detectable viral load
- willingness to participate in group sessions and have conversations with social
network members
Exclusion Criteria:
- participated in a behavioral intervention in prior 2 years
We found this trial at
1
site
Baltimore, Maryland 21205
Principal Investigator: Carl Latkin, PhD
Phone: 410-955-3972
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