A Phase 1b Study of MEDI4920 in Subjects With Adult-onset Rheumatoid Arthritis
Status: | Completed |
---|---|
Conditions: | Arthritis |
Therapuetic Areas: | Rheumatology |
Healthy: | No |
Age Range: | 18 - 70 |
Updated: | 8/30/2018 |
Start Date: | May 12, 2016 |
End Date: | August 9, 2018 |
A Phase 1b Randomized, Double-blind, Placebo-controlled Multiple-ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Immunogenicity, Pharmacodynamics, and Clinical Response of MEDI4920 in Subjects With Adult-onset Rheumatoid Arthritis
The purpose of this study is to determine whether MEDI4920 is safe and tolerable in patients
with adult-onset rheumatoid arthritis.
with adult-onset rheumatoid arthritis.
Inclusion Criteria:
- adult-onset rheumatoid arthritis
- swollen and tender joints
Exclusion Criteria:
- venous thromboembolism or arterial thrombosis
- pregnant or breastfeeding
- hepatitis B, C or HIV
- active or untreated latent tuberculosis
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