A Phase 1b Study of MEDI4920 in Subjects With Adult-onset Rheumatoid Arthritis



Status:Completed
Conditions:Arthritis
Therapuetic Areas:Rheumatology
Healthy:No
Age Range:18 - 70
Updated:8/30/2018
Start Date:May 12, 2016
End Date:August 9, 2018

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A Phase 1b Randomized, Double-blind, Placebo-controlled Multiple-ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Immunogenicity, Pharmacodynamics, and Clinical Response of MEDI4920 in Subjects With Adult-onset Rheumatoid Arthritis

The purpose of this study is to determine whether MEDI4920 is safe and tolerable in patients
with adult-onset rheumatoid arthritis.


Inclusion Criteria:

- adult-onset rheumatoid arthritis

- swollen and tender joints

Exclusion Criteria:

- venous thromboembolism or arterial thrombosis

- pregnant or breastfeeding

- hepatitis B, C or HIV

- active or untreated latent tuberculosis
We found this trial at
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Jacksonville, FL
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Anniston, AL
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Debary, FL
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Duncansville, Pennsylvania 16635
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