Neuropathic Pain in Pregnancy
| Status: | Active, not recruiting |
|---|---|
| Conditions: | Chronic Pain, Women's Studies |
| Therapuetic Areas: | Musculoskeletal, Reproductive |
| Healthy: | No |
| Age Range: | 18 - 45 |
| Updated: | 4/6/2019 |
| Start Date: | January 1, 2016 |
| End Date: | November 2, 2019 |
Neuropathic pain is a common pain disorder that is caused by problems in the nervous system.
It affects more women than men and commonly occurs in pregnancy. Physicians have little
information to guide their treatment of neuropathic pain in pregnancy. The overall goal of
this study is to define the course, management, and pregnancy outcomes of neuropathic pain in
pregnancy and the acute postpartum period. It is difficult to manage neuropathic pain in
pregnancy as treatment options must minimize their risk to the unborn child as they have a
direct effect on infant outcomes through their exposure in utero. Thus, other treatments are
needed. Repetitive transcranial magnetic stimulation (rTMS) may be an acceptable alternative
to medications. Transcranial magnetic stimulation uses a magnetic force to change the way
nerves work in the brain. This non-invasive and localized mechanism of action makes it
attractive for use in special populations, such as pregnancy. This will be the first study to
investigate the use of rTMS in the treatment of neuropathic pain in pregnancy. This study
will enroll 60 pregnant subjects between the ages of 18 and 45. Participation in the study
will last about 15 months with study visits about once a month. All participants will receive
treatment as usual. Subjects diagnosed with neuropathic pain will be offered rTMS as a
treatment option.
It affects more women than men and commonly occurs in pregnancy. Physicians have little
information to guide their treatment of neuropathic pain in pregnancy. The overall goal of
this study is to define the course, management, and pregnancy outcomes of neuropathic pain in
pregnancy and the acute postpartum period. It is difficult to manage neuropathic pain in
pregnancy as treatment options must minimize their risk to the unborn child as they have a
direct effect on infant outcomes through their exposure in utero. Thus, other treatments are
needed. Repetitive transcranial magnetic stimulation (rTMS) may be an acceptable alternative
to medications. Transcranial magnetic stimulation uses a magnetic force to change the way
nerves work in the brain. This non-invasive and localized mechanism of action makes it
attractive for use in special populations, such as pregnancy. This will be the first study to
investigate the use of rTMS in the treatment of neuropathic pain in pregnancy. This study
will enroll 60 pregnant subjects between the ages of 18 and 45. Participation in the study
will last about 15 months with study visits about once a month. All participants will receive
treatment as usual. Subjects diagnosed with neuropathic pain will be offered rTMS as a
treatment option.
Inclusion Criteria:
- age 18-45 years old,
- ability to give informed consent,
- viable pregnancy, and
- enrollment prior to or equal to 24 weeks gestation
Exclusion Criteria:
- Active or history of substance use disorder within the past year
- Non-English speaking
We found this trial at
1
site
529 West Markham Street
Little Rock, Arkansas 72205
Little Rock, Arkansas 72205
(501) 686-7000
Phone: 501-526-8201
University of Arkansas for Medical Sciences The University of Arkansas for Medical Sciences (UAMS) in...
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