The Active After Cancer Trial (AACT)



Status:Active, not recruiting
Conditions:Breast Cancer, Colorectal Cancer, Cancer, Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:18 - Any
Updated:8/30/2018
Start Date:October 2007
End Date:July 2020

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Pilot Study of a Multicenter, Telephone-Based Exercise Intervention for Patients With Early-Stage Breast and Colorectal Cancer: The Active After Cancer Trial (AACT)

This study is being done to determine whether a telephone-based counseling intervention can
help survivors of breast and colorectal cancer increase their weekly physical activity.
Observational evidence suggests that physical activity after breast and colorectal cancer
diagnosis decreases recurrence rates. Unfortunately, many people become less active during
cancer therapy, and a substantial proportion never return to pre-diagnosis levels of physical
activity. This study looks to see if people who have recently finished chemotherapy for
breast, colon or rectal cancer can be motivated to increase their exercise by talking to an
exercise specialist over the phone. The study also looks at changes in mood, fatigue,
fitness, fat distribution and weight.


Inclusion Criteria:

- Histologically confirmed stage I-III breast or colorectal cancer

- 18 years of age or older

- Completed adjuvant treatment(for current malignancy)

- Completion of all adjuvant chemotherapy and radiation (with the exception of adjuvant
herceptin and/or tamoxifen/aromatase inhibitor therapy for breast cancer patients)
between 2 and 36 months prior to enrollment

- Ability to speak and read English

- Willingness to be randomized

- Medical clearance from an oncologist or primary care physician stating the participant
is able to participate in an unsupervised, moderate-intensity physical activity
program

- No major surgery within 2 months of study enrollment or planned during study period

Exclusion Criteria:

- Metastatic cancer

- Uncontrolled intercurrent illness including, but not limited to, symptomatic
congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric
illness that would limit compliance with study requirements

- Plans to have hip or knee replacement within a year

- Participation in more than 60 minutes a week of moderate-intensity recreational
activity as assessed by the International Physical Activity Questionnaire Short Form

- BMI >47
We found this trial at
9
sites
Buffalo, New York 14263
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Buffalo, NY
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450 Brookline Ave
Boston, Massachusetts 2215
617-632-3000
Dana-Farber Cancer Institute Since it’s founding in 1947, Dana-Farber has been committed to providing adults...
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Boston, MA
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Burlington, Vermont 05405
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Burlington, VT
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281 W. Lane Ave
Columbus, Ohio 43210
(614) 292-6446
Ohio State University The Ohio State University’s main Columbus campus is one of America’s largest...
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Columbus, OH
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Concord, New Hampshire 03301
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Concord, NH
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East Syracuse, NY
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Hooksett, New Hampshire 03106
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Hooksett, NH
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9500 Gilman Dr
La Jolla, California 92093
(858) 534-2230
The University of California, San Diego UC San Diego is an academic powerhouse and economic...
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La Jolla, CA
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San Francisco, California 94143
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San Francisco, CA
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