Investigation of Human Laryngeal Evoked Brainstem Potentials
Status: | Recruiting |
---|---|
Healthy: | No |
Age Range: | 18 - 65 |
Updated: | 8/26/2018 |
Start Date: | June 2016 |
End Date: | June 2019 |
Contact: | Kristin Montella |
Email: | km302@nyumc.org |
The primary purpose of this study will be to determine whether the proposed study protocol
will allow for reliable detection of the human Laryngeal evoked brainstem responses (LEBR).
Laryngeal evoked brain stem responses will be recorded from five test subjects under general
anesthesia in the operating room with the assistance of an electrophysiologist with expertise
in evoked potentials. Once the feasibility of obtaining tracings are established on the first
few subjects, responses will be recorded from other test subjects with the aim of determining
the optimal placement of stimulating electrodes and detection leads necessary to elicit an
adequate response. The effect of varying the stimulus intensity will also be studied. Once
parameters for testing have been standardized, normative configurations for the laryngeal
evoked brainstem response tracings can be determined by patients both in the office setting
and in the operating room.
will allow for reliable detection of the human Laryngeal evoked brainstem responses (LEBR).
Laryngeal evoked brain stem responses will be recorded from five test subjects under general
anesthesia in the operating room with the assistance of an electrophysiologist with expertise
in evoked potentials. Once the feasibility of obtaining tracings are established on the first
few subjects, responses will be recorded from other test subjects with the aim of determining
the optimal placement of stimulating electrodes and detection leads necessary to elicit an
adequate response. The effect of varying the stimulus intensity will also be studied. Once
parameters for testing have been standardized, normative configurations for the laryngeal
evoked brainstem response tracings can be determined by patients both in the office setting
and in the operating room.
Inclusion Criteria:
- Healthy Subjects undergoing thyroid or other open neck surgeries
Exclusion Criteria:
- Current or recent (within one month) tracheostomy
- Vocal cord paralysis
- History of Stroke
- History of Diabetes Mellitus
- History of Neurologic Disease
- History of Radiation to the Neck
- History of Brain Surgery
- History of Neck Surgery
- Recent Laryngeal Surgery (within one month)
- Recent Intubation (within two weeks)
- Laryngopharyngeal Reflux Disease
- Allergy to Lidocaine
- Allergy to Oxymetazoline
We found this trial at
1
site
550 1st Ave
New York, New York 10016
New York, New York 10016
(212) 263-7300
Principal Investigator: Milam Amin, MD
New York University School of Medicine NYU School of Medicine has a proud history that...
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