Young Donor Plasma Transfusion and Age-Related Biomarkers
| Status: | Completed |
|---|---|
| Conditions: | Healthy Studies |
| Therapuetic Areas: | Other |
| Healthy: | No |
| Age Range: | 35 - Any |
| Updated: | 5/5/2018 |
| Start Date: | June 2016 |
| End Date: | January 15, 2018 |
The purpose of the study is to evaluate the beneficial effects of infusions of plasma from
young donors using blood biomarkers.
young donors using blood biomarkers.
Each patient will receive an infusion of plasma derived from a young donor (16-25 years of
age). A panel of age-associated biomarkers will be measured before and after treatment.
We have drawn biomarkers from clinical measures of aging and physiology, biomarkers of
disease advancement, as well as biomarkers of aging from animal and human studies. These will
represent a spectrum of physiologic pathways with evidence-based connections to aging. They
include the physiologic processes of inflammation, neurogenesis, stem cell proliferation,
blood clotting, immune function, and amyloid plaques. Organ function which will be
specifically measured includes the liver, bone marrow, kidneys, pancreas, muscles,
cardiovasculature, cerebrovasculature, and the thyroid. Specific disease states connected to
these biomarkers include anemia, neutropenia, thrombocytopenia, obesity, diabetes, high
cholesterol, elevated risk of cancer, atherosclerosis, dementia, and cataracts.
Visit us at www.ambrosiaplasma.com
age). A panel of age-associated biomarkers will be measured before and after treatment.
We have drawn biomarkers from clinical measures of aging and physiology, biomarkers of
disease advancement, as well as biomarkers of aging from animal and human studies. These will
represent a spectrum of physiologic pathways with evidence-based connections to aging. They
include the physiologic processes of inflammation, neurogenesis, stem cell proliferation,
blood clotting, immune function, and amyloid plaques. Organ function which will be
specifically measured includes the liver, bone marrow, kidneys, pancreas, muscles,
cardiovasculature, cerebrovasculature, and the thyroid. Specific disease states connected to
these biomarkers include anemia, neutropenia, thrombocytopenia, obesity, diabetes, high
cholesterol, elevated risk of cancer, atherosclerosis, dementia, and cataracts.
Visit us at www.ambrosiaplasma.com
Inclusion Criteria:
- 35 years of age or older
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