Biomarker Study in Participants With Migraine



Status:Completed
Conditions:Migraine Headaches
Therapuetic Areas:Neurology
Healthy:No
Age Range:Any
Updated:2/28/2019
Start Date:September 28, 2016
End Date:January 1, 2017

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LY2951742 Biomarker Study in Patients With Migraine

This is a study of participants with a diagnosis of migraine who completed another clinical
trial NTC02163993. The participants received either LY2951742 or placebo. This study
NCT02766517 will evaluate how certain biomarkers may be related to the participant's response
in study NTC02163993. The study will last about five days.


Inclusion Criteria:

- Participants with migraine who have previously participated in study NTC02163993 and
received one of the selected doses of galcanezumab or placebo

- Have suitable skin characteristics for the dermal capsaicin challenge

Exclusion Criteria:

- Have a history of significant allergies, in particular to ethanol or sensitivity to
the fruits of capsicum plants (for example, chili peppers)

- Have eczema, scleroderma, psoriasis, dermatitis, keloids, tumors, ulcers, burns,
flaps, or grafts on their forearm or other abnormality of the skin which may interfere
with the study assessments

- Cannot avoid excess tanning (any exposure to sunlight or a tanning bed which would
cause a sunburn reaction) throughout the study and cannot cover forearms for 24 hours
prior to each treatment period

- Have excessive hair growth on the volar surface of the forearm or participants
currently using lotions, oils, depilatory preparations, or other topical treatments on
a regular basis which cannot be discontinued for the duration of the study; has used
any topical treatments within 7 days of the start of the study
We found this trial at
14
sites
860 Peachwood Drive
DeLand, Florida 32720
(386) 740-0770
Site Overview Avail Clinical Research is a renowned and experienced clinical research site conducting Phase...
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Baltimore, Maryland 21225
Principal Investigator: S Marriot
Phone: 410-350-7979
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Baltimore, Maryland 21208
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Bellevue, Washington 98007
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Encino, California 91316
Principal Investigator: DANIEL GROSZ
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Glendale, California 91206
Principal Investigator: L Gertsik
Phone: 818-254-1600
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Los Alamitos, California 90720
Principal Investigator: Nader Oskooilar
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Memphis, Tennessee 38119
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Newport Beach, California 92660
Principal Investigator: Don De Francisco
Phone: 949-752-7910
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Phoenix, Arizona 85023
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Rochester, New York 14609
Principal Investigator: Matthew Davis
Phone: 716-288-8090
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San Diego, California 92108
Principal Investigator: William Koltun
Phone: 619-521-2830
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San Diego, California 92123
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