Development of a Tailored HIV Prevention Intervention for Young Men

A resurgence of new HIV cases among young men who have sex with men (YMSM; ages 18--24) has
underscored the importance of developing culturally- and developmentally- informed HIV
programs for YMSM. The investigators are developing and pilot testing a tailored, web- based
intervention called myDEx that focuses on delivering HIV prevention messages based on single
YMSM's relationship expectations and partner--seeking behaviors. To maximize intervention
appeal and appropriateness, the investigators have convened a youth advisory board (YAB) to
provide insight and feedback during the 3--stage intervention development process. Using an
iterative design and development process, they have developed tailored messages that align
YMSM's relationship experiences and desires with HIV prevention strategies. The
investigators designed and developed the myDEx tailored online prevention intervention, as
well as an attention- control non--tailored HIV/AIDS prevention (NTHP) comparison
intervention. After developing both interventions, the investigators used usability testing
procedures to collect preliminary data from 16 YMSM on the proposed intervention's design
and acceptability. Recommended changes were added to the intervention prior to launching a
small pilot randomized controlled trial (RCT). The pilot RCT will compare myDEx (N=120) to
NTHP (N=60) to assess intervention feasibility and acceptability, and gather preliminary
behavioral data to inform a subsequent application. Assessments will be collected at 30, 60,
and 90 days follow--up.

Specific Aims include:

1. To develop a tailored (myDEx) and non-tailored (NTHP) HIV prevention intervention
focused on addressing HIV risk behaviors among single YMSM;

2. To collect preliminary data on the feasibility, acceptability, and intervention content
of the myDEx (N=16) in preparation for a small pilot RCT; and,

3. To implement a small pilot RCT of the refined myDEx (N=120) as compared to the NTHP
(N=60) intervention, in order to evaluate its feasibility and acceptability and gather
preliminary efficacy results in reducing sexual risk behaviors.

Inclusion Criteria:

- Cis-gender male

- Self-report as being single

- Self report as HIV-negative at baseline

- Speak and read English

- Report unprotected anal intercourse with a male partner in prior six (6) months

- Have access to computer or smartphone device

Exclusion Criteria:

- Transgender identity

- HIV positive diagnosis

- Not residing in the United States

- Does not engage in male-to-male sexual behavior