Connectomics in Psychiatric Classification of Bipolar Disorder and Schizophrenia
| Status: | Recruiting |
|---|---|
| Conditions: | Schizophrenia, Psychiatric, Bipolar Disorder |
| Therapuetic Areas: | Psychiatry / Psychology |
| Healthy: | No |
| Age Range: | 18 - 30 |
| Updated: | 2/28/2019 |
| Start Date: | September 2014 |
| End Date: | September 2023 |
| Contact: | Christina Pritchard, LMSW |
| Email: | c.pritchard@wustl.edu |
| Phone: | 314-362-6952 |
Connectomics in Psychiatric Classification
Washington University Early Recognition Center is conducting a research study to examine
brain functional connectivity and network patterns in participants with bipolar disorder and
schizophrenia.
brain functional connectivity and network patterns in participants with bipolar disorder and
schizophrenia.
This study extends the assessment of brain connectivity and function, being conducted in the
Human Connectome Project (HCP), to psychiatrically ill populations. The HCP consortium has
made significant improvements in MRI instrumentation, data acquisition, preprocessing, and
analysis. These improvements are currently providing publicly available data on the
structure, function, and connectivity of young adult human (age 22-35) brains at
unprecedented spatial resolution, temporal resolution, and accuracy. This study will focus on
individuals aged 18-40 years who have a diagnosis of either schizophrenia/schizoaffective
disorder or bipolar disorder, or are healthy controls. Additionally, similar to the HCP, the
investigator will study the effect of genetics on the patterns of brain connectivity in
various psychiatric populations. DNA will be collected non-invasively from saliva.
Furthermore, this investigator will study cortisol levels in hair samples as an additional
assessment to help characterize brain imagining findings.
Human Connectome Project (HCP), to psychiatrically ill populations. The HCP consortium has
made significant improvements in MRI instrumentation, data acquisition, preprocessing, and
analysis. These improvements are currently providing publicly available data on the
structure, function, and connectivity of young adult human (age 22-35) brains at
unprecedented spatial resolution, temporal resolution, and accuracy. This study will focus on
individuals aged 18-40 years who have a diagnosis of either schizophrenia/schizoaffective
disorder or bipolar disorder, or are healthy controls. Additionally, similar to the HCP, the
investigator will study the effect of genetics on the patterns of brain connectivity in
various psychiatric populations. DNA will be collected non-invasively from saliva.
Furthermore, this investigator will study cortisol levels in hair samples as an additional
assessment to help characterize brain imagining findings.
Inclusion Criteria:
- Between ages 18-30
Exclusion Criteria:
- Head Injury
- Unstable Medical Condition
We found this trial at
1
site
660 S Euclid Ave
Saint Louis, Missouri 63110
Saint Louis, Missouri 63110
(314) 362-5000
Principal Investigator: Daniel Mamah, M.D., MPE
Phone: 314-362-6952
Washington University School of Medicine Washington University Physicians is the clinical practice of the School...
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