Registry of Amyloid Positive Patients for Alzheimer's Disease Drug Research Trials

Inclusion Criteria:

- Male or female patients ≥ 50 years of age at the time of consent;

- Patients who have objectively verified cognitive impairment and etiology diagnosed or
suspected to be Alzheimer's disease;

- Patients who are willing to make available to Avid a positive amyloid scan, or if an
amyloid scan is not available, are willing to undergo amyloid scanning via the
Florbetapir F 18 PET Scan Addendum;

- Patients who are willing to be contacted for possible participation in Lilly drug
research trials targeting Alzheimer's disease;

- Patients who give informed consent or have a legally authorized representative (LAR)
to consent for enrollment; and

- Patients who have a partner (informant) who is willing to participate as a source of
information and has at least weekly contact with the patient (contact can be inperson,
via telephone or electronic communication). The informant must have sufficient contact
such that the referring physician feels the informant can provide meaningful
information about the patient.

Exclusion Criteria:

- Patients who have a Mini Mental State Examination (MMSE) score of < 16;

- Patients who have an amyloid-negative PET scan (either a historical scan or scan via
the Florbetapir F 18 PET Scan Addendum);

- Patients who have serious or unstable medical conditions that would exclude completion
of all procedures and data collection for the registry, or would be likely to preclude
participation in a drug research trial;

- Patients who are currently participating in a clinical trial with an investigational
agent; or

- Patients who, in the opinion of the physician, are otherwise unsuitable for this
registry.