Open-label Study of Nelotanserin in Lewy Body Dementia With Visual Hallucinations or REM Sleep Behavior Disorder



Status:Terminated
Conditions:Alzheimer Disease, Parkinsons Disease, Neurology, Psychiatric
Therapuetic Areas:Neurology, Psychiatry / Psychology
Healthy:No
Age Range:50 - Any
Updated:3/29/2019
Start Date:October 20, 2016
End Date:January 17, 2019

Use our guide to learn which trials are right for you!

Trial Summary
Trial Overview
Inclusion Criteria

An Open-label Study of Nelotanserin in Patients With Lewy Body Dementia Who Have Frequent Visual Hallucinations or REM Sleep Behavior Disorder

This study seeks to evaluate the long-term safety and effectiveness of nelotanserin for the
treatment of visual hallucinations (VHs) and Rapid Eye Movement (REM) Sleep Behavior Disorder
(RBD) in subjects with Lewy body dementia (LBD).

This is a multi-center open-label, long-term study in LBD subjects with RBD and/or VHs.
Eligible subjects who completed a previous nelotanserin VH or RBD study and choose to
participate in this open-label study will receive 20, 40, 60, or 80 mg nelotanserin once
daily for 24 weeks.

Inclusion Criteria:

- Subjects with LBD who completed a previous nelotanserin VH or RBD study

Exclusion Criteria:

- Subjects with a current serious and/or unstable cardiovascular, respiratory, thyroid,
gastrointestinal, renal, hematologic or other medical disorder
We found this trial at
19
sites
US128
Memphis, Tennessee 38613
508
mi
from 43215
Memphis, TN
Click here to add this to my saved trials
US120
Birmingham, Alabama 35294
492
mi
from 43215
Birmingham, AL
Click here to add this to my saved trials
US114
114 Northwest Boca Raton Boulevard
Boca Raton, Florida 33486
955
mi
from 43215
Boca Raton, FL
Click here to add this to my saved trials
US101
101 Manning Drive
Chapel Hill, North Carolina 27514
354
mi
from 43215
Chapel Hill, NC
Click here to add this to my saved trials
US111
Cincinnati, Ohio 45229
94
mi
from 43215
Cincinnati, OH
Click here to add this to my saved trials
US104
Cleveland, Ohio 44195
129
mi
from 43215
Cleveland, OH
Click here to add this to my saved trials
US105
Columbus, Ohio 43210
2
mi
from 43215
Columbus, OH
Click here to add this to my saved trials
US147
Fargo, North Dakota 58103
838
mi
from 43215
Fargo, ND
Click here to add this to my saved trials
US107
Indianapolis, Indiana 46202
167
mi
from 43215
Indianapolis, IN
Click here to add this to my saved trials
US132
Lenexa, Kansas 66214
626
mi
from 43215
Lenexa, KS
Click here to add this to my saved trials
US129
129 Nebraska 2
Lincoln, Nebraska 68526
722
mi
from 43215
Lincoln, NE
Click here to add this to my saved trials
US173
Lincoln, Rhode Island 02865
?
mi
from 43215
Lincoln, RI
Click here to add this to my saved trials
US143
Little Rock, Arkansas 72205
623
mi
from 43215
Little Rock, AR
Click here to add this to my saved trials
US180
Maitland, Florida 32751
788
mi
from 43215
Maitland, FL
Click here to add this to my saved trials
US154
154 Old US Highway 301
Ocala, Florida 34471
744
mi
from 43215
Ocala, FL
Click here to add this to my saved trials
US113
Orlando, Florida 32806
797
mi
from 43215
Orlando, FL
Click here to add this to my saved trials
US152
Ormond Beach, Florida 32174
746
mi
from 43215
Ormond Beach, FL
Click here to add this to my saved trials
US103
Rochester, Minnesota 55905
563
mi
from 43215
Rochester, MN
Click here to add this to my saved trials
US131
131 Old Highway 90 West
San Antonio, Texas 78229
1141
mi
from 43215
San Antonio, TX
Click here to add this to my saved trials