Platelet-rich Plasma vs. Whole Blood for Gluteus Medius Tendinopathy
| Status: | Terminated |
|---|---|
| Conditions: | Orthopedic |
| Therapuetic Areas: | Orthopedics / Podiatry |
| Healthy: | No |
| Age Range: | 30 - 65 |
| Updated: | 8/9/2018 |
| Start Date: | October 1, 2013 |
| End Date: | June 2017 |
Ultrasound-Guided Platelet Rich Plasma Versus Whole Blood Injection for the Treatment of Gluteus Medius Tendinopathy: A Double-Blind Randomized Controlled Study
Gluteus medius tendinopathy, which is often referred to as Greater Trochanteric Pain
Syndrome, is characterized by pain in the lateral aspect of the hip that is aggravated by
side lying, stair climbing, and walking. Treatment is currently limited to lifestyle
modifications, corticosteroid injections, physical therapy, and open and endoscopic surgical
repair. Platelet rich plasma (PRP) injections contain important growth factors that are
essential in the healing and tissue formation processes. However, the extent to which PRP is
more efficacious than whole blood in tendinopathy remains unclear. In this double-blind
randomized trial, patients will be allocated to receive either a PRP or whole-blood
injection. Post-procedure assessments will occur at 6 weeks, 3 months, 6 months, 9 months,
and 1 year.
Syndrome, is characterized by pain in the lateral aspect of the hip that is aggravated by
side lying, stair climbing, and walking. Treatment is currently limited to lifestyle
modifications, corticosteroid injections, physical therapy, and open and endoscopic surgical
repair. Platelet rich plasma (PRP) injections contain important growth factors that are
essential in the healing and tissue formation processes. However, the extent to which PRP is
more efficacious than whole blood in tendinopathy remains unclear. In this double-blind
randomized trial, patients will be allocated to receive either a PRP or whole-blood
injection. Post-procedure assessments will occur at 6 weeks, 3 months, 6 months, 9 months,
and 1 year.
Inclusion Criteria:
- Moderate to severe lateral hip pain for greater than 3 months
- Symptoms are refractory to conservative treatment, including at least 8 weeks of
traditional physical therapy for this condition
- Moderate to severe gluteus medius tendinosis with or without partial tear <1 cm
- Normal neurologic exam except for hip abductor weakness on the affected side
Exclusion Criteria:
- Severe (Tonnis grade >1) hip osteoarthritis with active synovitis or bone edema
- Active lumbar radiculopathy with pain, numbness or weakness in a dermatomal
distribution
- No evidence of fatty atrophy, denervation, or complete tears of gluteus medius seen on
MRI
- Any condition that requires anti-platelet or anti-coagulation therapy, including
aspirin therapy for cardiac conditions
- Non-English speaking
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Hospital for Special Surgery Founded in 1863, Hospital for Special Surgery is the nation
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