Risk Factors for Quinolone Resistance Among ESBL Producing Klebsiella Species

This is a retrospective chart review. This proposed study aims to document the risk factors
for quinolone resistance in bloodstream isolates of Klebsiella species. Additionally, the
adequacy of empiric antibiotic therapy for Klebsiella bloodstream infections will be
assessed. This research is (c) important because identification of risk factors may allow
earlier initiation of appropriate therapy in patients infected with these bacteria.
Additionally, we will identify whether horizontal spread is responsible for this increasing
trend.

Inclusion Criteria:

- must be quinolone resistant among ESBL producing klebsiella species

Exclusion Criteria:

- Those not meeting entry criteria