The Crnic Institute Human Trisome Project Biobank

The purpose of this study is to provide qualified and approved researchers with access to
biological samples and health information to answer specific research questions. This project
will significantly increase the speed of Down syndrome research and the understanding of
associated medical conditions such as Alzheimer's disease, congenital heart defects,
autoimmune disorders, autism, and some forms of leukemia.

Participation includes a blood draw, a mouth swab, and allowing researchers to look at your
health information yearly for the next 5 years. Optional procedures include providing a urine
and/or stool sample and taking part in the study for a longer time frame.

Inclusion Criteria:

Anyone 6 months to 89 years old who:

1. has Down syndrome (any type)

2. does not have Down syndrome

Exclusion Criteria:

1. Prisoners

2. Wards of the state