Selegiline Transdermal System for the Treatment of Cocaine Dependence - 1

The study objectives are to assess the efficacy and safety of the Selegiline Transdermal
System (STS) in reducing cocaine use in subjects with cocaine dependence. It is hypothesized
that selegiline treatment compared to placebo, will be associated with fewer days of cocaine
use as assessed by self-report confirmed with urine assays for benzoylecgonine (BE).

Inclusion Criteria:

- Male/Female

- At least 18 years of age

- DSM-4 diagnosis of cocaine dependence

- Ability to understand and provide written consent

- Female subjects must use acceptable birth control

Exclusion Criteria:

- Additional Criteria available during the screening process at the site.