Diagnosing Respiratory Disease in Children Using Cough Sounds
| Status: | Completed |
|---|---|
| Conditions: | Asthma, Asthma, Bronchitis, Pneumonia, Infectious Disease, Pulmonary, Pulmonary |
| Therapuetic Areas: | Immunology / Infectious Diseases, Pulmonary / Respiratory Diseases |
| Healthy: | No |
| Age Range: | Any - 12 |
| Updated: | 1/7/2018 |
| Start Date: | December 2016 |
| End Date: | December 2017 |
Diagnosing Respiratory Disease in Children Using Smartphone Recordings of Cough Sounds
The purpose of this prospective study is to evaluate the efficacy of the ResAppDx software
application in diagnosis of pneumonia and other respiratory conditions (bronchiolitis,
asthma/reactive airway disease, croup, upper or lower respiratory tract infections) in
infants and children. Patient's cough sounds will be recorded using a smartphone and analysed
using the ResAppDx software. The ResAppDx diagnosis will be compared to radiologic diagnosis
and/or clinical diagnosis. The ResAppDx diagnosis will not be provided to the clinician or
patient.
application in diagnosis of pneumonia and other respiratory conditions (bronchiolitis,
asthma/reactive airway disease, croup, upper or lower respiratory tract infections) in
infants and children. Patient's cough sounds will be recorded using a smartphone and analysed
using the ResAppDx software. The ResAppDx diagnosis will be compared to radiologic diagnosis
and/or clinical diagnosis. The ResAppDx diagnosis will not be provided to the clinician or
patient.
Inclusion Criteria:
- Infant or child aged 29 days - 12 years
- Presenting to the study site with signs or symptoms of respiratory disease including
cough, wheezing, stridor, chest in-drawing/retractions, difficulty breathing, fast
breathing, abnormal lung sounds on exam, cyanosis/hypoxemia.
- Coughing spontaneously or able to cough voluntarily
Exclusion Criteria:
- Lack of a signed consent form from parent or legal guardian
- Lack of signed assent form for children aged 7 years or older who, in the opinion of
the investigator, is able to provide assent based on their age, maturity or
psychological state.
- Need for mechanical ventilatory support (including invasive, continuous positive
airway pressure, or bilevel positive airway pressure) or high flow nasal cannula
- Any medical contraindication to voluntary cough, including (only enrolled if coughing
spontaneously): severe respiratory distress, history of pneumothorax,
eye/chest/abdominal surgery in past 3 months, hemoptysis in the past month, or too
medically unstable to participate in study per treating clinician.
- Subject previously enrolled
- Tracheostomy present or tube placed
We found this trial at
3
sites
185 Cambridge Street
Boston, Massachusetts 02114
Boston, Massachusetts 02114
617-724-5200
Principal Investigator: Peter P Moschovis, MD MPH
Phone: 617-643-9687
Click here to add this to my saved trials
Cleveland, Ohio
Principal Investigator: John C Carl, MD
Phone: 216-444-3916
Click here to add this to my saved trials
6621 Fannin St
Houston, Texas 77030
Houston, Texas 77030
(832) 824-1000
Principal Investigator: Esther M Sampayo, MD MPH
Phone: 832-824-6512
Texas Children's Hospital Texas Children's Hospital, located in Houston, Texas, is a not-for-profit organization whose...
Click here to add this to my saved trials