Serotonin/Dopamine Antagonism of Cocaine Effect: 2 - 2
| Status: | Terminated |
|---|---|
| Conditions: | Psychiatric, Pulmonary |
| Therapuetic Areas: | Psychiatry / Psychology, Pulmonary / Respiratory Diseases |
| Healthy: | No |
| Age Range: | 18 - 50 |
| Updated: | 1/13/2017 |
| Start Date: | January 1996 |
| End Date: | March 1996 |
Serotonin/Dopamine Antagonism of Cocaine Effect
The purpose of this study is to evaluate use of risperidone with cocaine abusers. Study
measures incorporate an appropriate integration of behavioral and neurobiological indices.
measures incorporate an appropriate integration of behavioral and neurobiological indices.
Risperidone in low doses is compared with placebo in a 6-week randomized trial. Subjects
also receive supportive counseling. Outcome measure include rating of behavior, mood, drug
abuse, global function, and urine toxicology.
also receive supportive counseling. Outcome measure include rating of behavior, mood, drug
abuse, global function, and urine toxicology.
Inclusion Criteria:
Cocaine abuse or dependence
Exclusion Criteria:
Dependence on other drugs. Major psychiatric illness
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