Buprenorphine Formulation Comparison: Sublingual Tablet vs. Solution - 1



Status:Completed
Conditions:Gastrointestinal
Therapuetic Areas:Gastroenterology
Healthy:No
Age Range:18 - 65
Updated:1/13/2017
Start Date:October 1997
End Date:August 1999

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Trial Summary
Trial Overview
Inclusion Criteria

Buprenorphine Formulation Comparison: Sublingual Tablet vs. Solution

The purpose of this study is to compare subject response to liquid vs. tablet formulations,
to assess bioequivalency of liquid vs. tablet, to compare subject preference, and to
evaluate if dose response curve for tablet is equal to liquid form."

1) Compare subjects response to liquid vs tablet formulation 2) Assess bioequivalency of
liquid vs tablet 3)Compare subject preference 4) Evaluate if dose response curve for tablet
= to liquid form

Inclusion Criteria:

M/F ages 18-65. Meet DMS-IV criteria for opiate dependence. Agree to conditions of the
study and sign informed consent.

Exclusion Criteria:

Pregnant or nursing women. Acute medical condition that would interfere with study
participation or put safety of subjects in jeopardy. Current daily use of
anti-convulsants, antabuse or neuroleptics. DSM-IV diagnosis of ETOH or sedative/hypnotics
dependence.
We found this trial at
1
site
Friends Research Institute
Los Angeles, California 90025
?
mi
from
Los Angeles, CA
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