Selegiline in Outpatient Treatment for Cocaine Dependence - 1
| Status: | Completed |
|---|---|
| Conditions: | Psychiatric, Pulmonary |
| Therapuetic Areas: | Psychiatry / Psychology, Pulmonary / Respiratory Diseases |
| Healthy: | No |
| Age Range: | 21 - 50 |
| Updated: | 1/13/2017 |
| Start Date: | January 1995 |
| End Date: | March 1996 |
Safety and Efficacy of Selegiline in Outpatient Treatment for Cocaine
The purpose of this study is to evaluate the efficacy and clinical safety of selegiline in
the treatment of cocaine dependence and to assess neurotoxicity (Magnetic Resonance Imaging,
MRI) post-hoc as a possible variable for future stratification in clinical trials.
the treatment of cocaine dependence and to assess neurotoxicity (Magnetic Resonance Imaging,
MRI) post-hoc as a possible variable for future stratification in clinical trials.
Inclusion Criteria:
M/F ages 21-50. Meets DSM-IV criteria for cocaine. Agreeable to conditions of study and
signed informed consent.
Exclusion Criteria:
Psychiatric disorder that requires medication therapy. History of seizures. Pregnant
and/or nursing women. Dependence on ETOH or benzodiazepines or other sedative/hypnotics.
Acute hepatitis. Other medical conditions that deem participation to be unsafe.
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