Optical Coherence Tomography (OCT) Intravascular Ultrasound (IVUS) Dual Imaging
| Status: | Active, not recruiting |
|---|---|
| Conditions: | Peripheral Vascular Disease, Cardiology |
| Therapuetic Areas: | Cardiology / Vascular Diseases |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 9/28/2017 |
| Start Date: | October 2016 |
| End Date: | September 2018 |
Dual Imaging Using High-definition Intravascular Ultrasound and Optical Coherence Tomography to Guide Percutaneous Coronary Intervention
Both intravascular ultrasound (IVUS) and optical coherence tomography (OCT) are standardly
used and have been extensively studied separately to guide percutaneous coronary intervention
and improve long-term outcomes. In this study, the investigators aim to directly compare
high-definition IVUS images to OCT in the same patients to determine the differences between
each modality as they relate to imaging coronary pathology, with the goal of determining
which modality is most appropriate in particular clinical scenarios.
used and have been extensively studied separately to guide percutaneous coronary intervention
and improve long-term outcomes. In this study, the investigators aim to directly compare
high-definition IVUS images to OCT in the same patients to determine the differences between
each modality as they relate to imaging coronary pathology, with the goal of determining
which modality is most appropriate in particular clinical scenarios.
Intravascular ultrasound (IVUS) is an imaging modality that uses ultrasound waves to allow
for detailed evaluation of coronary atherosclerotic plaques and the vascular response to
coronary interventional devices to guide stent placement during percutaneous coronary
intervention. Current conventional IVUS catheters emit ultrasound waves ranging from 20-40
megahertz (mHz), and more recently released high-definition IVUS catheters emit sound waves
at 60 mHz, allowing for better image quality, quantitative accuracy, and precision in
measurements.
Optical coherence tomography (OCT) is an alternative imaging modality used for similar
purposes as IVUS, using a single optical fiber that emits infrared light to image the
coronary artery. OCT uses light in the infrared spectrum with a central wavelength between
1,250 and 1,350 nm. Axial resolution with OCT is 10-20 microns, whereas it is typically
100-200 microns with IVUS. Thus, OCT allows for better image resolution, but this comes at
the expense of tissue penetration.
for detailed evaluation of coronary atherosclerotic plaques and the vascular response to
coronary interventional devices to guide stent placement during percutaneous coronary
intervention. Current conventional IVUS catheters emit ultrasound waves ranging from 20-40
megahertz (mHz), and more recently released high-definition IVUS catheters emit sound waves
at 60 mHz, allowing for better image quality, quantitative accuracy, and precision in
measurements.
Optical coherence tomography (OCT) is an alternative imaging modality used for similar
purposes as IVUS, using a single optical fiber that emits infrared light to image the
coronary artery. OCT uses light in the infrared spectrum with a central wavelength between
1,250 and 1,350 nm. Axial resolution with OCT is 10-20 microns, whereas it is typically
100-200 microns with IVUS. Thus, OCT allows for better image resolution, but this comes at
the expense of tissue penetration.
Inclusion criteria:
- Undergone diagnostic coronary angiography
- Evidence of coronary pathology that requires further imaging to guide treatment
Exclusion criteria:
Significant renal insufficiency
We found this trial at
1
site
116th St and Broadway
New York, New York 10027
New York, New York 10027
(212) 854-1754
Phone: 212-305-7060
Columbia University In 1897, the university moved from Forty-ninth Street and Madison Avenue, where it...
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