Follow up 18F-AV-1451 Scan in Confirmatory Cohort Subjects From Study 18F-AV-1451-A05



Status:Completed
Conditions:Alzheimer Disease
Therapuetic Areas:Neurology
Healthy:No
Age Range:50 - Any
Updated:10/27/2018
Start Date:August 2016
End Date:August 28, 2017

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Trial Summary
Trial Overview
Inclusion Criteria

An Open Label, Multicenter Study Evaluating the Imaging Characteristics of a Follow up 18F-AV-1451 Scan in Subjects That Participated in the Confirmatory Cohort of 18F-AV-1451-A05

This study will evaluate longitudinal change of tau deposition as measured by 18F-AV-1451
uptake over time.


Inclusion Criteria:

- Confirmatory cohort subjects who completed the 18F-AV-1451-A05 (NCT02016560) study

Exclusion Criteria:

- Current clinically significant cardiovascular disease, ECG abnormalities, risk factors
for Torsades de Pointes (TdP), or are taking drugs know to cause QT prolongation

- Current clinically significant infectious disease, endocrine or metabolic disease,
pulmonary, renal or hepatic impairment, or cancer

- Females of childbearing potential who are not surgically sterile, not refraining from
sexual activity or not using reliable methods of contraception

- Have had a non-study related radiopharmaceutical imaging or treatment procedure within
7 days prior to the study imaging session

- Have received or participated in a trial with investigational medications in the past
30 days
We found this trial at
22
sites
Meridien Research
Saint Petersburg, Florida 33709
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Massachusetts General Hospital
185 Cambridge Street
Boston, Massachusetts 02114
617-724-5200
Principal Investigator: Keith Johnson, MD
Phone: 617-724-7066
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Boston, MA
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Boston University School of Medicine
72 East Concord Street
Boston, Massachusetts 02118
(617) 638-5300
Principal Investigator: Robert Stern, PhD
Phone: 617-638-5368
Boston University School of Medicine A leader in medical education and research, Boston University School...
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Boston, MA
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Compass Research LLC
100 West Gore St # 202
Orlando, Florida 32806
(407) 426-9299
Principal Investigator: Craig Curtis, MD
Phone: 407-426-9299
Compass Research LLC Compass Research is a clinical research company dedicated to testing new medications...
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Orlando, FL
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Rhode Island Hospital
593 Eddy Street
Providence, Rhode Island 02903
401-444-4000
Principal Investigator: Brian Ott, MD
Phone: 401-444-6440
Rhode Island Hospital Founded in 1863, Rhode Island Hospital in Providence, RI, is a private,...
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Providence, RI
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Duke Univ Med Ctr
2301 Erwin Rd
Durham, North Carolina 27710
919-684-8111
Principal Investigator: Murali Doraiswamy, MD
Phone: 919-684-5933
Duke Univ Med Ctr As a world-class academic and health care system, Duke Medicine strives...
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Durham, NC
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Neuropsychiatric Research Center of Southwest Florida
Fort Myers, Florida 33912
Principal Investigator: Frederick Schaerf, MD
Phone: 239-939-7777
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Fort Myers, FL
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Institute for Brain Aging and Dementia, UC Irvine
Irvine, California 92697
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Irvine, CA
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Las Vegas Radiology
Las Vegas, Nevada 89113
Principal Investigator: Bharat Mocherla, MD
Phone: 702-666-6066
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Las Vegas, NV
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New York University Center for Brain Health
560 1st Avenue
New York, New York 10016
Principal Investigator: Tracy Butler, MD
Phone: 646-248-6734
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New York, NY
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21st Century Oncology
11190 Warner Avenue
Newport Beach, California 92663
Principal Investigator: William Shankle, MD
Phone: 949-478-8858
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Newport Beach, CA
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Univ of Pennsylvania
3451 Walnut St
Philadelphia, Pennsylvania 19104
1 (215) 898-5000
Principal Investigator: David Wolk, MD
Phone: 215-573-7495
Univ of Pennsylvania Penn has a long and proud tradition of intellectual rigor and pursuit...
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Philadelphia, PA
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Banner Alzheimer'S Institute
Phoenix, Arizona 85006
Principal Investigator: Pierre Tariot, MD
Phone: 617-638-5368
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Phoenix, AZ
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Butler Hospital
345 Blackstone Blvd
Providence, Rhode Island 02906
(401) 455-6200
Principal Investigator: Stephen Salloway, MD
Phone: 401-455-6403
Butler Hospital Founded in 1844, Butler Hospital is the state's only non-profit, free-standing psychiatric hospital...
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Providence, RI
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Alzheimer's Disease Center, UC Davis
2315 Stockton Boulevard
Sacramento, California 95817
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Sacramento, CA
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Washington University School of Medicine
660 S Euclid Ave
Saint Louis, Missouri 63110
(314) 362-5000
Principal Investigator: Tammie Benzinger, MD
Phone: 314-362-1558
Washington University School of Medicine Washington University Physicians is the clinical practice of the School...
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Saint Louis, MO
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California Medical Clinic for Headache
Santa Monica, California 90404
Principal Investigator: David Kudrow, MD
Phone: 310-315-1456
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Santa Monica, CA
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Imaging Endpoints
9700 North 91st Street
Scottsdale, Arizona 85258
Principal Investigator: Ronald Korn, MD
Phone: 480-425-4170
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Scottsdale, AZ
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Mayo Clinic Arizona
13400 E. Shea Blvd.
Scottsdale, Arizona 85259
480-301-8000
Mayo Clinic Arizona Mayo Clinic in Arizona provides medical care for thousands of people from...
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Scottsdale, AZ
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Banner Sun Health Research Institute
Sun City, Arizona 85351
Principal Investigator: Edward Zamrini, MD
Phone: 623-832-6530
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Sun City, AZ
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University of South Florida Health Byrd Alzheimer's Institute
4001 East Fletcher Avenue
Tampa, Florida 33613
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Tampa, FL
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Premiere Research Institute
West Palm Beach, Florida 33407
Principal Investigator: Carl Sadowsky, MD
Phone: 561-845-0500
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West Palm Beach, FL
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