Home-Based Exercise Program For Recovery After Transcatheter Aortic Valve Replacement

Status:	Recruiting
Conditions:	Cardiology
Therapuetic Areas:	Cardiology / Vascular Diseases
Healthy:	No
Age Range:	65 - Any
Updated:	1/26/2019
Start Date:	August 1, 2017
End Date:	December 31, 2019
Contact:	Dae Hyun Kim, MD, MPH, ScD
Email:	dkim2@bidmc.harvard.edu
Phone:	6176328696

Home-Based Exercise Program For Recovery After Transcatheter Aortic Valve Replacement: A Pilot Study

Transcatheter aortic valve replacement (TAVR) is a minimally invasive procedure for older
adults with severe symptomatic aortic stenosis who are considered high risk for surgical
aortic valve replacement. Despite symptomatic and survival benefits, many patients experience
functional decline after TAVR. This pilot study aims to test the feasibility of a home-based
exercise intervention targeting endurance, strength, and balance as well as cognitive
behavioral intervention to improve physical functioning and disability after TAVR.

We hypothesize that a home-based exercise program with cognitive behavioral intervention is
more effective than home-based exercise alone; home-based exercise program with and without
cognitive behavioral intervention is more effective than attention control educational
intervention in preventing decline in physical function and disability after TAVR.

Inclusion Criteria:

- Age ≥ 65 years

- Underwent transcatheter aortic valve replacement

- Lives within 20-mile radius of the recruiting site

- Plan to be discharged home

- Able to provide informed consent

Exclusion Criteria:

- Stroke or any other medical disease that precludes participation in the exercise
program

- Severe cognitive impairment (Mini-Mental State Examination < 15)

- Current enrollment in another clinical trial

We found this trial at

sites

Beth Israel Deaconess Medical Center

330 Brookline Ave
Boston, Massachusetts 02215

617-667-7000