Study With Seletracetam (Ucb 44212) in Adult Subjects (18 to 65 Years) With Partial Onset Seizures

Inclusion Criteria:

- Males/Females from 18 to 65 years of age (minimum body weight of 40 kg)

- Subjects with a confirmed diagnosis of epilepsy suffering from partial onset seizures
whether or not secondarily generalized.

- Subjects who have been treated for epilepsy for ≥6 months and are currently
uncontrolled while being treated with 1-3 concomitant AED(s).

- Female subjects without childbearing potential; Female subjects with childbearing
potential are eligible if they use a medically accepted non-hormonal contraceptive
method

Exclusion Criteria:

- Seizures occurring in clusters. Status epilepticus within 6 months of Visit 1.
History of non-epileptic seizures

- Subjects on vigabatrin

- Subjects on felbamate, unless treatment has been continuous for >2 years

- Ongoing psychiatric disease other than mild controlled disorders.

- Subjects with clinically significant organ dysfunction

- Known allergic reaction or intolerance to pyrrolidine derivatives and/or excipients

- Pregnant or lactating women.

- Subjects currently taking levetiracetam (LEV).

- Use of benzodiazepines (for any indication) taken at a higher frequency than an
average of once a week, unless counted as one of the concomitant AEDs.