Effect of Repaglinide and Metformin Combination Tablet or Rosiglitazone and Metformin in Fixed Dose Combination on Blood Glucose Control in Patients With Type 2 Diabetes



Status:Completed
Conditions:Diabetes, Diabetes
Therapuetic Areas:Endocrinology
Healthy:No
Age Range:18 - Any
Updated:2/11/2017
Start Date:November 2006
End Date:November 2007

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Trial Summary
Trial Overview
Inclusion Criteria

Repaglinide and Metformin Combination Tablet (NN4440) in a TID Regimen Compared to a BID Regimen and BID Avandamet in Subjects With Type 2 Diabetes: A Twenty-Six Week, Open-Label, Multicenter, Randomized, Parallel Group Trial to Investigate Efficacy and Safety

This trial is conducted in the United States of America (USA). This trial compares the
changes in HbA1c after 26 weeks of repaglinide and metformin fixed dose combination tablet
given as twice daily versus three times daily regimens or versus twice daily rosiglitazone
and metformin fixed dose combination tablet in subjects with type 2 diabetes currently on
monotherapy.


Inclusion Criteria:

- Type 2 diabetes for at least 3 months

- HbA1c between 7.5-11.0% on monotherapy or

- HbA1c between 7.0-10.0% on dual therapy

- BMI maximum 45 kg/m2

Exclusion Criteria:

- Any clinically significant disease history in the opinion of the investigator

- Severe heart disease

- Pregnancy
We found this trial at
94
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Bossier City, Louisiana 71111
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Ann Arbor, Michigan 48106
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Arlington Heights, Illinois 60004
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Asheville, North Carolina 28801
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Atlanta, Georgia 30318
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Aurora, Illinois 60506
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Aventura, Florida 33180
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Baltimore, Maryland 21229
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Berlin, New Jersey 08009
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Chicago, Illinois 60612
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Chula Vista, California 91910
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Cincinnati, Ohio 45229
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Clearwater, Florida 33756
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Colorado Springs, Colorado 80910
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Columbus, Georgia 31904
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Corpus Christi, Texas 78404
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Cranston, Rhode Island 02920
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Dallas, Texas 75231
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Daytona Beach, Florida 32117
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Des Moines, Iowa 50314
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East Providence, Rhode Island 02914
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Erlanger, Kentucky 41018
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Flint, Michigan 48504
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Flossmoor, Illinois 60422
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Franklin, Ohio 45005
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Glendale, Arizona 85306
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Greenville, North Carolina 27834
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Greer, South Carolina 29651
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Hamden, Connecticut 06518
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Henrico, Virginia 23233
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Honolulu, Hawaii 96814
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Houston, Texas 77030
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Hyattsville, Maryland 20782
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Indianapolis, Indiana 46260
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Inverness, Florida 34452
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Jacksonville, Florida 32207
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Jersey City, New Jersey 07306
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Jonesboro, Arkansas 72401
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Kansas City, Missouri 64106
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Kingsport, Tennessee 37660
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Knoxville, Tennessee 37938
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Las Vegas, Nevada 89128
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Lebanon, Virginia 24266
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Long Beach, California 90807
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Longwood, Florida 32779
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Los Angeles, California 90027
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Louisville, Kentucky 40213
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Marietta, Georgia 30060
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Mesa, Arizona 85206
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Midland, Texas 79707
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Milwaukee, Wisconsin 53209
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Mt. Pleasant, South Carolina 29464
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Nampa, Idaho 83686
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Naperville, Illinois 60564
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Norristown, Pennsylvania 19401
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Oak Brook, Illinois 60523
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Oak Park, Michigan 48237
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Ocala, Florida 34471
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Omaha, Nebraska 68114
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Orlando, Florida 32804
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Philadelphia, Pennsylvania 19104
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Plano, Texas 75075
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Plantation, Florida 33324
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Portland, Oregon 97239
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Poway, California 92064
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Raleigh, North Carolina 27610
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Redlands, California 92374
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Richmond, Virginia 23219
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Rochester, New York 14609
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Sacramento, California 95821
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Salisbury, North Carolina 28144
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San Antonio, Texas 78224
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San Diego, California 92111
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San Juan, 00921
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San Mateo, California 94401
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Shawnee Mission, Kansas 66204
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Simpsonville, South Carolina 29681
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Spring Valley, California 91978
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Springfield, Illinois 62702
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Springfield, Pennsylvania 19064
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St. George, Utah 84790
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Stamford, Connecticut 06905
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Tampa, Florida 33612
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Topeka, Kansas 66606
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Troy, Michigan 48098
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Tulsa, Oklahoma 74135
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Vernon Hills, Illinois 60061
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Vestavia, Alabama 35209
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Virginia Beach, Virginia 23454
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Warren, New Jersey 07059
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West Palm Beach, Florida 33409
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West Seneca, New York 14224
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Wilmington, North Carolina 28401
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Winston-Salem, North Carolina 27103
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