The MOTS (Medication Overuse Treatment Strategy) Trial
| Status: | Enrolling by invitation |
|---|---|
| Conditions: | Migraine Headaches |
| Therapuetic Areas: | Neurology |
| Healthy: | No |
| Age Range: | 21 - Any |
| Updated: | 4/6/2019 |
| Start Date: | January 9, 2017 |
| End Date: | April 30, 2021 |
Determining the Optimal Treatment Strategy for Patients Who Have Chronic Migraine With Medication Overuse
There are two commonly used treatment strategies for treating patients who have chronic
migraine with medication overuse. This study will compare the outcomes amongst patients
randomized to one of the two treatment strategies.
migraine with medication overuse. This study will compare the outcomes amongst patients
randomized to one of the two treatment strategies.
Inclusion Criteria
- Adults, at least 21 years of age
- Chronic Migraine - diagnosed according to ICHD3beta criteria
- Medication Overuse - diagnosed according to ICHD3beta criteria
- Willingness to be randomized to either of the two treatment arms
- Willingness to maintain a headache diary
- Plan for follow-up care with the clinician
- No changes to migraine prophylactic therapy within the 4 weeks prior to randomization.
Exclusion Criteria
- Younger than 21 years of age
- Headache diagnoses other than chronic migraine with medication overuse; episodic
tension-type headache on 3 or fewer days per month is allowed
- Not willing to be randomized to either of the treatment arms
- Not willing to maintain a daily headache diary
- Not planning on follow-up care with the clinician
- In the opinion of the clinician, randomization to either treatment arm would be
considered unsafe (ex: pregnancy, immediate discontinuation
- Prisoners
- Diminished decision-making capacity which in the investigator's opinion would
interfere with the person's ability to provide informed consent and complete study
procedures.
We found this trial at
31
sites
Cleveland Clinic Cleveland Clinic is committed to principles as presented in the United Nations Global...
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1601 Northwest 12th Avenue
Miami, Florida 33136
Miami, Florida 33136
(305) 243-6545
University of Miami Miller School of Medicine The University of Miami Leonard M. Miller School...
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111 s South 11th Street
Philadelphia, Pennsylvania 19107
Philadelphia, Pennsylvania 19107
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