Adductor Canal Block Versus Periarticular Bupivicaine Injection in Total Knee Arthroplasty



Status:Completed
Conditions:Arthritis, Osteoarthritis (OA)
Therapuetic Areas:Rheumatology
Healthy:No
Age Range:Any
Updated:3/22/2019
Start Date:July 19, 2016
End Date:November 1, 2017

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The objective of the study is to compare the efficacy of adductor canal blocks versus
periarticular bupivacaine injections for pain management in total knee arthroplasty. This
randomized clinical trial will compare outcomes between adductor canal blocks, periarticular
bupivacaine injections, and periarticular liposomal bupivacaine injections. Results from this
study will help determine the most appropriate perioperative pain management strategy for
patients undergoing a total knee arthroplasty.

Over 600,000 total knee arthroplasties (TKAs) are performed each year in the United States,
with expectations for greater than 4 million/year by the year 2030. Since the onset of TKAs
in the 1960's, there have been developments that have improved both functionality and patient
satisfaction. In the last decade, a focus has been made on multimodal pain management
protocols, more rapid functional recovery, reduced length of hospital stay, and minimizing
side effects of treatment while maintaining function and durability. The widespread use of
regional anesthesia has led to improvements in pain control, more rapid functional recovery,
and reduced length of stay. In recent years many surgeons have transitioned from femoral
nerve blocks (proximal femoral nerve) to adductor canal blocks (distal femoral nerve) to
maintain a sensory block for pain control, while minimizing any motor blockade that is
typically seen in proximal femoral nerve blocks, which would hamper rehabilitation, and
increase risk of falls. In addition to regional blocks, which are typically performed in the
preoperative setting, some surgeons favor an intraoperative periarticular anesthetic
injection (PAI), typically with bupivacaine or the long acting form liposomal bupivacaine,
either in conjunction with an adductor canal block, or independently. In theory, PAI has the
advantage of a comparable sensory nerve block as an adductor canal block, without the
disadvantages and risks, which include prolonged quadriceps weakness, fall risk, and
neurologic dysfunction.

The purpose of this randomized control trial is to compare the efficacy of adductor canal
blocks versus periarticular bupivacaine injections for pain management in total knee
arthroplasty.

Inclusion Criteria:

- Patients undergoing an unilateral primary total knee arthroplasty under the care of the
two senior arthroplasty surgeons.

Exclusion Criteria:

- Allergy to bupivicaine or liposomal bupivicaine.
We found this trial at
1
site
630 W 168th St
New York, New York
212-305-2862
Principal Investigator: Jeffrey Geller, MD
Phone: 212-305-8193
Columbia University Medical Center Situated on a 20-acre campus in Northern Manhattan and accounting for...
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mi
from
New York, NY
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