Effect of Inhaled Insulin (AERx® iDMS) on Blood Glucose Control in Type 2 Diabetes



Status:Terminated
Conditions:Diabetes, Diabetes
Therapuetic Areas:Endocrinology
Healthy:No
Age Range:18 - Any
Updated:9/7/2018
Start Date:November 29, 2006
End Date:March 18, 2008

Use our guide to learn which trials are right for you!

Trial Summary
Trial Overview
Inclusion Criteria

Effect of Inhaled Insulin (AERx® iDMS) Plus Pioglitazone Versus Pioglitazone Alone on HbA1c in Subjects With Type 2 Diabetes

This trial is conducted in the United States of America (USA). This trial will compare the
changes in HbA1c after 26 weeks of inhaled insulin and pioglitazone combination therapy
versus pioglitazone treatment alone.

The decision to discontinue the development of AERx® is not due to any safety concerns. An
analysis concluded that fast-acting inhaled insulin in the form it is known today, is
unlikely to offer significant clinical or convenience benefits over injections of modern
insulin with pen devices.

Inclusion Criteria:

- Type 2 diabetes

- Current treatment with oral antidiabetes drugs (OADs) for at least 2 months

- HbA1c between 7.0-11.0% if on OAD monotherapy

- HbA1c between 7.0-10.0% if on OAD combination therapy

- BMI less than or equal to 40 kg/m2

Exclusion Criteria:

- Current regular smoking or regular smoking within the last 6 months

- Current acute or chronic pulmonary disease (except for asthma)

- Proliferative retinopathy requiring treatment

- Clinically significant disease history including kidney or liver disease, or heart
disease which limits physical activity or results in discomfort with physical activity

- Pregnancy
We found this trial at
103
sites
Novo Nordisk Investigational Site
Beverly Hills, Florida 34465
?
mi
from
Beverly Hills, FL
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Altoona, Pennsylvania 16602
?
mi
from
Altoona, PA
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Arlington, Texas 76012
?
mi
from
Arlington, TX
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Arlington, Virginia 22206
?
mi
from
Arlington, VA
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Arvada, Colorado 80005
?
mi
from
Arvada, CO
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Athens, Georgia 30606
?
mi
from
Athens, GA
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Atlanta, Georgia 30318
?
mi
from
Atlanta, GA
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Avon, Illinois 46123
?
mi
from
Avon, IL
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Baltimore, Maryland 21229
?
mi
from
Baltimore, MD
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Beaver, Pennsylvania 15009
?
mi
from
Beaver, PA
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Bensalem, Pennsylvania 19020
?
mi
from
Bensalem, PA
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Bermuda Dunes, California 92203
?
mi
from
Bermuda Dunes, CA
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Billings, Montana 59101
?
mi
from
Billings, MT
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Bismarck, North Dakota 58501
?
mi
from
Bismarck, ND
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Bloomington, Minnesota 55420
?
mi
from
Bloomington, MN
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Blue Ridge, Georgia 30513
?
mi
from
Blue Ridge, GA
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Boca Raton, Florida 33433
?
mi
from
Boca Raton, FL
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Boise, Idaho 83712
?
mi
from
Boise, ID
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Canal Fulton, Ohio 44614
?
mi
from
Canal Fulton, OH
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Charlotte, North Carolina 28277
?
mi
from
Charlotte, NC
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Chesterfield, Missouri 63017
?
mi
from
Chesterfield, MO
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Chicago, Illinois 60612
?
mi
from
Chicago, IL
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Cincinnati, Ohio 45229
?
mi
from
Cincinnati, OH
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Clarksville, Tennessee 37043
?
mi
from
Clarksville, TN
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Clearwater, Florida 33756
?
mi
from
Clearwater, FL
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Cleveland, Ohio 44106
?
mi
from
Cleveland, OH
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Clinton, Oklahoma 73601
?
mi
from
Clinton, OK
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Colorado Springs, Colorado 80910
?
mi
from
Colorado Springs, CO
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Dallas, Texas 75231
?
mi
from
Dallas, TX
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Dayton, Ohio 45406
?
mi
from
Dayton, OH
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Des Moines, Iowa 50314
?
mi
from
Des Moines, IA
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Dunwoody, Georgia 30338
?
mi
from
Dunwoody, GA
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Escondido, California 92025
?
mi
from
Escondido, CA
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Fresno, California 93702
?
mi
from
Fresno, CA
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Greer, South Carolina 29651
?
mi
from
Greer, SC
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Hershey, Pennsylvania 17033
?
mi
from
Hershey, PA
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Hialeah, Florida 33012
?
mi
from
Hialeah, FL
Click here to add this to my saved trials
Novo Nordisk Investigational Site
High Point, North Carolina 27265
?
mi
from
High Point, NC
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Hollywood, Florida 33024
?
mi
from
Hollywood, FL
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Honolulu, Hawaii 96814
?
mi
from
Honolulu, HI
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Houston, Texas 77030
?
mi
from
Houston, TX
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Huntington Beach, California 92648
?
mi
from
Huntington Beach, CA
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Jackson, Mississippi 39209
?
mi
from
Jackson, MS
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Jefferson City, Missouri 65109
?
mi
from
Jefferson City, MO
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Kansas City, Missouri 64106
?
mi
from
Kansas City, MO
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Kingsport, Tennessee 37660
?
mi
from
Kingsport, TN
Click here to add this to my saved trials
Novo Nordisk Investigational Site
La Jolla, California 92037
?
mi
from
La Jolla, CA
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Lafayette, Indiana 47904
?
mi
from
Lafayette, IN
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Lake Mary, Florida 32746
?
mi
from
Lake Mary, FL
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Las Vegas, Nevada 89128
?
mi
from
Las Vegas, NV
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Lewisville, Texas 75067
?
mi
from
Lewisville, TX
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Lexington, Kentucky 40503
?
mi
from
Lexington, KY
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Little Rock, Arkansas 72202
?
mi
from
Little Rock, AR
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Marianna, Florida 32446
?
mi
from
Marianna, FL
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Marlborough, Massachusetts 01752
?
mi
from
Marlborough, MA
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Medford, Oregon 97501
?
mi
from
Medford, OR
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Melbourne, Florida 32901
?
mi
from
Melbourne, FL
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Miami, Florida 33136
?
mi
from
Miami, FL
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Niceville, Florida 32578
?
mi
from
Niceville, FL
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Norfolk, Virginia 23510
?
mi
from
Norfolk, VA
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Norristown, Pennsylvania 19401
?
mi
from
Norristown, PA
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Northridge, California 91325
?
mi
from
Northridge, CA
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Oklahoma City, Oklahoma 73112
?
mi
from
Oklahoma City, OK
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Orange, California 92868
?
mi
from
Orange, CA
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Ozark, Alabama 36360
?
mi
from
Ozark, AL
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Palm Harbor, Florida 34684
?
mi
from
Palm Harbor, FL
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Panama City, Florida 32401
?
mi
from
Panama City, FL
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Pembroke Pines, Florida 33026
?
mi
from
Pembroke Pines, FL
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Peoria, Illinois 61615
?
mi
from
Peoria, IL
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Plano, Texas 75075
?
mi
from
Plano, TX
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Poway, California 92064
?
mi
from
Poway, CA
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Powder Springs, Georgia 30127
?
mi
from
Powder Springs, GA
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Prince Frederick, Maryland 20678
?
mi
from
Prince Frederick, MD
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Raleigh, North Carolina 27610
?
mi
from
Raleigh, NC
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Richmond, Virginia 23219
?
mi
from
Richmond, VA
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Roseville, California 95661
?
mi
from
Roseville, CA
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Roswell, Georgia 30076
?
mi
from
Roswell, GA
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Sacramento, California 95821
?
mi
from
Sacramento, CA
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Saint George, Utah 84790
?
mi
from
Saint George, UT
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Saint Louis, Missouri 63110
?
mi
from
Saint Louis, MO
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Saint Petersburg, Florida 33713
?
mi
from
Saint Petersburg, FL
Click here to add this to my saved trials
Novo Nordisk Investigational Site
San Antonio, Texas 78224
?
mi
from
San Antonio, TX
Click here to add this to my saved trials
Novo Nordisk Investigational Site
San Diego, California 92111
?
mi
from
San Diego, CA
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Sandy Springs, Georgia 30328
?
mi
from
Sandy Springs, GA
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Santa Barbara, California 93105
?
mi
from
Santa Barbara, CA
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Suwanee, Georgia 30024
?
mi
from
Suwanee, GA
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Syracuse, New York 13210
?
mi
from
Syracuse, NY
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Tacoma, Washington 98405
?
mi
from
Tacoma, WA
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Tallahassee, Florida 32308
?
mi
from
Tallahassee, FL
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Temecula, California 92591
?
mi
from
Temecula, CA
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Topeka, Kansas 66606
?
mi
from
Topeka, KS
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Tucker, Georgia 30084
?
mi
from
Tucker, GA
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Tucson, Arizona 85704
?
mi
from
Tucson, AZ
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Tuscaloosa, Alabama 35406
?
mi
from
Tuscaloosa, AL
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Tustin, California 92780
?
mi
from
Tustin, CA
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Vero Beach, Florida 32960
?
mi
from
Vero Beach, FL
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Vestavia Hills, Alabama 35209
?
mi
from
Vestavia Hills, AL
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Walnut Creek, California 94598
?
mi
from
Walnut Creek, CA
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Waltham, Massachusetts 02453
?
mi
from
Waltham, MA
Click here to add this to my saved trials
Novo Nordisk Investigational Site
Warrenton, Virginia 20186
?
mi
from
Warrenton, VA
Click here to add this to my saved trials
Novo Nordisk Investigational Site
West Palm Beach, Florida 33409
?
mi
from
West Palm Beach, FL
Click here to add this to my saved trials