Cancer & Chemotherapy Symptom Management Using an Automated Telephone Reporting System

The purpose of this study was to test the efficacy of a computer-based automated symptom
monitoring telephone system used by patients who received chemotherapy for their cancer to
communicate unrelieved symptoms they experienced to their oncology providers. The symptoms
monitored in the project were nausea/vomiting, pain, sore mouth, diarrhea, constipation,
depressed mood, anxiety, trouble sleeping, and fatigue. The study randomly assigned
participants into either the intervention group or the group that received usual care from
their oncology providers without alert notifications. All participants called the automated
system daily to report their symptom presence, severity, and distress. When participants in
the intervention group rated symptoms at moderate (4-7) to severe (8-10) levels an e-mail
alert report of their symptom information was sent to the participant's medical oncologist
and oncology nurse. The usual care group also reported symptoms daily to the automated
system but their information was not sent to the providers. Participants in the usual care
group were told daily to call their oncology provider if they had concerns about their
symptoms. The two study groups were compared over chemotherapy cycles 2 and 3 on symptom
presence, severity, and distress. Functional status, patient reported degree of symptom
interference with normal activities, and work attendance if they had indicated that they
worked during their treatment were also recorded. In addition, the groups were compared for
the number and purpose of unscheduled patient-provider contacts, visits to the emergency
department or urgent care facility, and unscheduled hospitalizations.

Inclusion Criteria:

- Adult (18 or older)

- Histological Diagnosis of Cancer

- Life Expectancy of at least 6 months

- Cognitively able to participate (verified by provider team)

- Initiated a course of new Chemotherapy that is planned for a minimum of 3 cycles

- Had Poorly controlled symptoms during the first cycle of chemotherapy

- Care under the direction of one of the designated provider teams

- English or Spanish speaking

- Has access to a telephone on a daily basis

- Able to use the telephone unassisted

Exclusion Criteria:

- Receiving concurrent radiation therapy because they would be in daily contact with
oncology care providers.

- Patients seeing the provider team for recommendation of chemotherapy regimen but
other providers then administer treatment at different site

- Patients receiving a treatment regimen with only biotherapy agents or agents not
associated with the symptoms monitored