Mobile Enhancement of Motivation in Schizophrenia



Status:Completed
Conditions:Schizophrenia, Psychiatric, Psychiatric
Therapuetic Areas:Psychiatry / Psychology
Healthy:No
Age Range:18 - Any
Updated:8/1/2018
Start Date:February 28, 2017
End Date:January 16, 2018

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Mobile Enhancement of Motivation in Schizophrenia: A Pilot Trial of a Personalized Text Message Intervention for Motivation Deficits

Motivation deficits are a strong determinant of poor functional outcomes in people with
schizophrenia. Mobile interventions are a promising approach to improving these deficits, as
they can provide frequent cues and reinforcements that support goal-directed behavior. The
primary aims of this study are to conduct a pilot study using a randomized design to 1) Test
the feasibility and acceptability of a personalized mobile text message intervention, Mobile
Enhancement of Motivation in Schizophrenia (MEMS) and to 2) Test the preliminary
effectiveness of MEMS compared to a control condition.

Objectives: Motivation deficits are one of the strongest determinants of poor functional
outcomes in people with schizophrenia. Mobile interventions are a promising approach to
improving these deficits, as they can provide frequent cues and reinforcements that support
goal-directed behavior. The objective of this study is to conduct a pilot study using a
randomized design to 1) Test the feasibility and acceptability of a personalized mobile text
message intervention, Mobile Enhancement of Motivation in Schizophrenia (MEMS) and to 2) Test
the preliminary effectiveness of MEMS compared to a control condition. Methods: Up to forty
outpatients with a schizophrenia-spectrum disorder will be recruited. All participants will
set individualized recovery goals to complete over an eight-week period; those randomized to
receive MEMS will also receive three sets of personalized, interactive text messages each
weekday to reinforce and cue goal completion. Before and after the eight-week period,
participants in both groups will complete validated measures of motivation. Both groups will
also report their goal attainment after eight weeks. Results: It is anticipated that those in
the MEMS group will demonstrate greater goal attainment and improvements in motivation
compared to the control group. Discussion: This project will test the initial feasibility,
acceptability, and effectiveness of a novel intervention for improving one of the most
debilitating aspects of schizophrenia.

Inclusion Criteria:

- Schizophrenia-spectrum diagnosis

- Have a text-message enabled cell-phone

- Are a current client at a participating community mental health center

- Are in a non-acute phase of illness or have no medication changes or hospitalizations
in the prior 30 days

- Demonstrate a minimum of moderate motivation impairments according to the Clinical
Assessment Interview for Negative Symptoms (CAINS; Kring et al., 2013)

- Have an English reading level at or above the fourth grade according to the Graded
Word List (Pray & Ross, 1969)
We found this trial at
1
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Indianapolis, Indiana 46208
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Indianapolis, IN
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