Magnetic Resonance-guided High-Intensity Focused Ultrasound (MR-HIFU) Used for Mild Hyperthermia



Status:Not yet recruiting
Conditions:Colorectal Cancer, Cervical Cancer, Cervical Cancer, Cancer, Cancer, Cancer, Cancer, Infectious Disease, Women's Studies, Bladder Cancer
Therapuetic Areas:Immunology / Infectious Diseases, Oncology, Reproductive
Healthy:No
Age Range:18 - Any
Updated:5/20/2017
Start Date:June 30, 2017
End Date:June 30, 2018
Contact:Michael Altman, Ph.D.
Email:m.altman@wustl.edu
Phone:(314) 362-4818

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A Feasibility Study of Magnetic Resonance-guided High-Intensity Focused Ultrasound (MR-HIFU) Used for Mild Hyperthermia in Human Subjects

This study will help to elucidate the treatment sites in the extremities and pelvis for
which MR-guided HIFU heating is feasible, which has the potential to be beneficial for
patients with conditions at those sites (soft tissue sarcoma, cervical cancer, etc.). The
investigators anticipate that successful completion of this study will lead to clinical
trials in those feasible sites of interest to determine the safety and efficacy of
administering therapeutic levels of heat for hyperthermia or other applications.


Inclusion Criteria:

- At least 18 years of age

- Willing and able to provide informed consent

- Patients only: must have a tumor in extremity muscle tissue or in the pelvis.

Exclusion Criteria:

- Contraindications for MRI (e.g., unsafe MRI implanted devices, shrapnel, history of
metal fragments in eyes, neurostimulators, excessive size and weight, claustrophobia)

- Pregnant
We found this trial at
1
site
660 S Euclid Ave
Saint Louis, Missouri 63110
(314) 362-5000
Principal Investigator: Michael Altman, Ph.D.
Phone: 314-362-4818
Washington University School of Medicine Washington University Physicians is the clinical practice of the School...
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