PRESSUREwire Study

The purpose of this study is to understand routine use of FFR and alternate indices in
clinical practice. This study will determine the use and clinical outcome of FFR-guided PCI
in patients presenting with either stable coronary artery disease, or in patients presenting
with Acute Coronary Syndrome (ACS) on culprit and non-culprit lesions as well as during index
and secondary procedures.

The study will also collect data on the routine use of coronary physiologic measurements such
as adenosine-induced hyperemia FFR, FFR by contrast-induced hyperemia,

Inclusion Criteria:

- Patient is presenting with STEMI, NSTEMI, unstable angina, or stable coronary artery
disease

- Patient is planned to have FFR performed or underwent a cardiac catheterization where
FFR was performed for further PCI (Percutaneous Cardiac Intervention) consideration

- Patient signs and dates written informed consent

- Patient is eighteen years of age or older at the time of consent

Exclusion Criteria:

- Patient has extremely tortuous or calcified coronary arteries

- Patient with a patent coronary artery bypass graft to the target vessel