Measurement of Anterior Chamber Cell Grading Using Ocular Coherence Tomography



Status:Terminated
Conditions:Cervical Cancer, Ocular
Therapuetic Areas:Oncology, Ophthalmology
Healthy:No
Age Range:18 - Any
Updated:3/16/2019
Start Date:September 2016
End Date:April 2018

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Objective, Prospective Measurement of Anterior Chamber Cell Grading Using Anterior Chamber Ocular Coherence Tomography

Optical Coherence Tomography (OCT) is routinely used in ophthalmic clinical practice. It uses
infrared light to image patient's eyes. Some patients, such as those with an inflammatory
disease called uveitis or those who have just undergone cataract surgery, have intraocular
inflammation. This intraocular inflammation commonly manifests as cells that can be seen on
routine microscopic clinical examination. However, the only currently available method to
quantify this intraocular inflammation is by manually counting on the microscopic clinical
examination. The investigators plan to use the OCT machine to image patient's eyes. The
investigators will then use the images obtained from the OCT to objectively quantify the
degree of intraocular inflammation.


Inclusion Criteria:

- Age over 18 years old

- Intervention Arm:

- Active anterior chamber inflammation in at least one eye as diagnosed by clinical
exam

- One of the following: 1) diagnosis of uveitis OR 2) undergone cataract extraction
surgery within the previous 30 days

- Control Arm:

- No active intraocular inflammation based on clinical exam

Exclusion Criteria:

- Corneal opacities in the affected eye

- Anyone judged unable to understand or consent to study participation
We found this trial at
1
site
90 Bergen Street
Newark, New Jersey 07101
Phone: 973-972-2037
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mi
from
Newark, NJ
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