A Study of ADX-102 in Subjects With Allergic Conjunctivitis



Status:Completed
Conditions:Allergy, Ocular
Therapuetic Areas:Ophthalmology, Otolaryngology
Healthy:No
Age Range:18 - Any
Updated:3/7/2019
Start Date:December 2016
End Date:May 2017

Use our guide to learn which trials are right for you!

A Multi-Center, Double-Masked, Randomized, Vehicle-Controlled, Phase 2b Evaluation of the
Onset and Duration of ADX-102 Ophthalmic Drops (0.5% and 0.1%) Compared to Vehicle of ADX-102
Ophthalmic Drops in the Conjunctival Allergen Challenge (Ora-CAC®) Model of Acute Allergic
Conjunctivitis.


Inclusion Criteria:

- be at least 18 years of age of either gender and any race

- have a positive history of ocular allergies and a positive skin test reaction to a
seasonal (grasses, ragweed, and/or trees) or perennial allergen (cat dander, dog
dander, dust mites, cockroach) as confirmed by an allergic skin test within the past
24 months

- have a calculated visual acuity of 0.7 logMAR or better in each eye as measured using
an ETDRS chart

Exclusion Criteria:

- have known contraindications or sensitivities to the use of the investigational
product or any of its components

- have any ocular condition that, in the opinion of the investigator, could affect the
subject's safety or trial parameters (including but not limited to narrow angle
glaucoma, clinically significant blepharitis, follicular conjunctivitis, iritis,
pterygium or a diagnosis of dry eye)

- have had ocular surgical intervention within three (3) months prior to Visit 1 or
during the study and/or a history of refractive surgery within the past six (6) months

- have a known history of retinal detachment, diabetic retinopathy, or active retinal
disease

- have the presence of an active ocular infection (bacterial, viral or fungal) or
positive history of an ocular herpetic infection at any visit

- be a female who is currently pregnant, planning a pregnancy, lactating, not using a
medically acceptable form of birth control throughout the study duration and for 14
days prior to the installation of investigational product, or has a positive urine
pregnancy test at Visit 1
We found this trial at
4
sites
?
mi
from
Morrow, GA
Click here to add this to my saved trials
?
mi
from
Mason, OH
Click here to add this to my saved trials
?
mi
from
Memphis, TN
Click here to add this to my saved trials
?
mi
from
Philadelphia, PA
Click here to add this to my saved trials