Adaptive Treatment for Adolescent Anorexia Nervosa
| Status: | Recruiting |
|---|---|
| Conditions: | Psychiatric, Psychiatric, Eating Disorder |
| Therapuetic Areas: | Psychiatry / Psychology |
| Healthy: | No |
| Age Range: | 12 - 18 |
| Updated: | 12/21/2018 |
| Start Date: | September 1, 2017 |
| End Date: | April 1, 2022 |
| Contact: | Alex M L'Insalata, BA |
| Email: | alinsalata@stanford.edu |
| Phone: | 6507239182 |
Confirming the Efficacy/Mechanism of an Adaptive Treatment for Adolescent Anorexia
The investigators are conducting a randomized controlled trial using an adaptive design for
adolescents (ages 12-18) with anorexia nervosa to compare standard Family Based Treatment
(FBT) to adaptive FBT with an Intensive Parental Coaching (IPC) component. If participants do
not reach expected milestones by session 4 of treatment, participants may be randomized to
receive additional IPC or continue treatment as usual with regular FBT.
adolescents (ages 12-18) with anorexia nervosa to compare standard Family Based Treatment
(FBT) to adaptive FBT with an Intensive Parental Coaching (IPC) component. If participants do
not reach expected milestones by session 4 of treatment, participants may be randomized to
receive additional IPC or continue treatment as usual with regular FBT.
Potential subjects aged 12 to 18 with anorexia nervosa (AN) will be recruited from Stanford
University, University of California, San Francisco, and other bay-area medical programs and
clinics. If participants are deemed eligible, participants will be invited for a baseline
interview (about 2 hours in duration) during which the investigators will conduct interviews
and collect questionnaire measures. Then, participants and participants' families will begin
Family Based Treatment (FBT) with a study therapist at Stanford University or University of
California, San Francisco, respectively.
At session 4, if participants have not gained 2.4kg, an indicator of early treatment
response, participants and participants' families will be randomized to receive either
treatment as usual (FBT) or an adaptive form of FBT, during which families will receive
additional Intensive Parental Coaching (IPC). If participants have reached weight milestones
(i.e., 2.4kg at session 4), participants will continue FBT as usual.
At 3 months of treatment and end of treatment, the investigators will collect the same
measures taken at baseline. The investigators also ask that families participate in 6- and
12-month follow-up, respectively.
University, University of California, San Francisco, and other bay-area medical programs and
clinics. If participants are deemed eligible, participants will be invited for a baseline
interview (about 2 hours in duration) during which the investigators will conduct interviews
and collect questionnaire measures. Then, participants and participants' families will begin
Family Based Treatment (FBT) with a study therapist at Stanford University or University of
California, San Francisco, respectively.
At session 4, if participants have not gained 2.4kg, an indicator of early treatment
response, participants and participants' families will be randomized to receive either
treatment as usual (FBT) or an adaptive form of FBT, during which families will receive
additional Intensive Parental Coaching (IPC). If participants have reached weight milestones
(i.e., 2.4kg at session 4), participants will continue FBT as usual.
At 3 months of treatment and end of treatment, the investigators will collect the same
measures taken at baseline. The investigators also ask that families participate in 6- and
12-month follow-up, respectively.
Inclusion Criteria:
- 12-18 years of age and living with participants' families
- meeting DSM-5 criteria for AN (both subtypes) except for the amenorrhea requirement
- medically stable for outpatient treatment according to the recommended thresholds of
the American Academy of Pediatrics and the Society of Adolescent Medicine.
Exclusion Criteria:
- associated physical illness that necessitates hospitalization
- psychotic illness, mental retardation, or any other mental illnesses that would
prohibit the use of psychotherapy
- current dependence on drugs or alcohol
- physical conditions (e.g. diabetes mellitus, pregnancy) known to influence eating or
weight
- previous FBT
- currently taking medication for co-morbid disorders that cannot be safely discontinued
on a stable dose for less than 2 months
- in the case of patients with current, or a history of sexual or physical abuse by
family members, perpetrators of the abuse will be excluded from treatment.
We found this trial at
2
sites
Click here to add this to my saved trials
291 Campus Dr
Stanford, California 94305
Stanford, California 94305
(650) 725-3900
Phone: 650-723-9182
Stanford University School of Medicine Vast in both its physical scale and its impact on...
Click here to add this to my saved trials