Patient Function/Fitness and Psychosocial Health in Improving Health-Related Quality of Life in Patients With Stage I-IV Non-Small Cell Lung Cancer

PRIMARY OBJECTIVES:

I. To determine the correlation of patient-reported health-related quality of life (HRQOL)
outcomes with clinical/treatment variables as well as a panel of both function/fitness and
psychosocial health assessments in non-small cell lung cancer (NSCLC).

SECONDARY OBJECTIVES:

I. To investigate the panel of function/fitness and psychosocial health assessments with
patient's smoking history/status as a predictor for treatment related toxicity.

TERTIARY OBJECTIVES:

I. The documentation of the NSCLC lung population from this prospective combined with others.

OUTLINE:

Patients scheduled for surgery, radiation therapy, or chemotherapy complete the European
Organization for Research and Treatment of Cancer (EORTC) quality of life questionnaire
(QLQ)-core 30 (C30) and QLQ-Lung Cancer 13 (LC13) in addition to psychosocial health and
smoking status questions from baseline up to 2 weeks prior to the start of treatment, 5-6
weeks after treatment begins, and 5-6 months from the start of treatment. During the same
time points, patients also undergo function/fitness assessments including standard health
measurements, short physical performance battery (SPPB), 6 minute walk test (6MWT), and a
grip strength test.

After completion of study treatment, patients are followed up every 3-6 months.

Inclusion Criteria:

- Newly diagnosed lung cancer

Exclusion Criteria:

- Previous or active lung cancer treatment at the time of registration