Effect of Dietary Fat on Glycemic Control in Type 1 Diabetes
| Status: | Completed |
|---|---|
| Conditions: | Diabetes |
| Therapuetic Areas: | Endocrinology |
| Healthy: | No |
| Age Range: | 18 - 75 |
| Updated: | 4/27/2017 |
| Start Date: | September 2010 |
| End Date: | September 2011 |
Use of Closed Loop Control to Examine the Effect of Changes in Dietary Fat Intake on Insulin Requirements and Glucose Control
The purpose of this study is to determine if dietary fat alters insulin requirements in type
1 diabetes.
1 diabetes.
This cross-over prospective study will require a two day admission to the clinical research
center. Subjects will undergo closed loop glucose control and will received a diet with
controlled macronutrient content.
center. Subjects will undergo closed loop glucose control and will received a diet with
controlled macronutrient content.
Inclusion Criteria:
- type 1 diabetes using insulin pump and CGM
Exclusion Criteria:
- renal or hepatic failure
- cancer or lymphoma
- malabsorption or malnourishment
- hypercortisolism
- alcoholism or drug abuse
- anemia (hematocrit < 36 in females and <40 in males)
- eating disorder
- dietary restrictions
- Acetaminophen allergy
- Chronic acetaminophen use
- Glucocorticoid therapy
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Beth Israel Deaconess Medical Center Beth Israel Deaconess Medical Center (BIDMC) is one of the...
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