Preoperative Acetaminophen and Carbohydrate Loading



Status:Completed
Conditions:Skin Cancer, Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:18 - Any
Updated:2/8/2018
Start Date:July 1, 2016
End Date:December 31, 2017

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Impact of Preoperative Acetaminophen and Carbohydrate Loading to on Pain and Functional Status in Patients Undergoing Mohs Micrographic Surgery for Non-melanoma Skin Cancers

The study's goal is to assess impact of preoperative acetaminophen and oral carbohydrate
drinks on pain and functional status experienced by patients undergoing Mohs micrographic
surgery for non-melanoma skin cancers. Patients are randomly assigned to receive standard of
care or preoperative acetaminophen 1000 mg and Gatorade sports drinks 2 packets before
surgery. Patients are then asked to rate their level of pain, anxiety, thirst, hunger,
fatigue on a scale of 0-100 on day of surgery before surgery has started, after clearance of
skin cancer, and at the end of the visit. Patients are contacted by phone 48 hours after
their surgery to assess their maximum level of post-operative pain (rated from 0-100), usage
of over the counter or prescribed pain medications, and presence of complications e.g.
bleeding, infection, dehiscence. Differences in perioperative functional status and pain
medication usage are compared between patients in control and intervention groups.


Inclusion Criteria:

- Adult patients undergoing Mohs micrographic surgery for non-melanoma skin cancers
(basal cell carcinoma and squamous cell carcinoma)

Exclusion Criteria:

- history of liver transplant, hepatitis, or cirrhosis, those required to be NPO for
subsequent closure by other surgical specialties, or those with known allergy to
acetaminophen
We found this trial at
1
site
260 Tremont Street
Boston, Massachusetts 02111
?
mi
from
Boston, MA
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