Enhancing Medication-based Analgesia in Humans



Status:Recruiting
Conditions:Chronic Pain
Therapuetic Areas:Musculoskeletal
Healthy:No
Age Range:18 - 75
Updated:12/14/2018
Start Date:December 2016
End Date:September 2019
Contact:Kelly E Dunn, PhD
Email:kdunn9@jhmi.edu
Phone:410-550-2254

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Trial Summary
Trial Overview
Inclusion Criteria
This research is being done to evaluate whether combining medications that are FDA approved
but have not yet been approved for combination treatment, can be an effective way to reduce
pain.

This study will systematically evaluate whether a combination of pharmacotherapies can
effectively alleviate chronic pain. Subjects will complete a screening session before
completing 5 study sessions that will occur once weekly. Subjects will double-blind doses of
study medications the morning of each experimental session, and will undergo standardized
pain testing, as well as provide self-report ratings of drug effects, and cognitive tests.

Inclusion Criteria:

- Not pregnant or breast feeding

- Medically cleared to take blinded study medications

- Willing to comply with study protocol

Exclusion Criteria:

- Not experiencing and/or being treated for current pain

- Lack of significant medical or psychiatric illness that would interfere with study
participation or informed consent

- Known allergy to the blinded study medications
We found this trial at
1
site
Johns Hopkins University
3400 N Charles St
Baltimore, Maryland 21205
410-516-8000
Phone: 410-550-9799
Johns Hopkins University The Johns Hopkins University opened in 1876, with the inauguration of its...
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mi
from
Baltimore, MD
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