A Study to Evaluate the Change in Weight After 24 Weeks Treatment With LIK066 in Obese or Overweight Adults
| Status: | Completed |
|---|---|
| Conditions: | Obesity Weight Loss |
| Therapuetic Areas: | Endocrinology |
| Healthy: | No |
| Age Range: | 18 - 75 |
| Updated: | 1/19/2019 |
| Start Date: | May 6, 2017 |
| End Date: | August 2, 2018 |
A Randomized, Double-blind, Dose-finding Study to Evaluate the Change in Weight After 24 Weeks Treatment With 8 Doses of LIK066 Compared to Placebo in Obese or Overweight Adults, Followed by 24 Weeks Treatment With 2 Doses of LIK066 and Placebo
This is a dose-finding study to evaluate the change in weight after 24 weeks treatment with 8
different doses of LIK066 compared to placebo in obese or overweight adults, followed by 24
weeks treatment with 2 doses of LIK066 and placebo.
different doses of LIK066 compared to placebo in obese or overweight adults, followed by 24
weeks treatment with 2 doses of LIK066 and placebo.
Inclusion Criteria:
1. informed consent
2. (BMI>=30) or (BMI>=27 with history of CV disease, hypertension, dyslipidemia,
pre-diabetes or type 2 diabetes mellitus, sleep-apnea syndrome)
3. willing to comply with life-style intervention and treatment during the full duration
of the study (approximately 54 weeks)
Exclusion Criteria:
- Hypersensitivity to any of the study medications
- Pregnancy or lactating women
- History of malignancies
- Use of pharmacologically active weight loss products
- Bariatric surgery
- Ketoacidosis, lactic acidosis, hyperosmolar coma in the 6 months before the screening
visit.
- HbA1c >10% at the screening visit.
We found this trial at
56
sites
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Novartis Novartis, which was created in 1996 by the merger of the Swiss companies Ciba-Geigy...
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