A Feasibility Registry of Actigraphy Monitoring in Degenerative Mitral Regurgitation Subjects Receiving the MitraClip® Device

This is a prospective, open-label, and multi-centered feasibility registry (single arm
study). Approximately 36 subjects with prohibitive risk degenerative mitral regurgitation
(DMR) who receive at least 1 commercial MitraClip will be registered at up to 10 US sites.

Inclusion Criteria:

- Subject must consent to receiving the MitraClip device

- Subject must consent, be able, and commit to wearing the Actiwatch continuously for
approximately 7 months

- Subject must consent to use of their data from this registry for purposes of
exploratory research and publication and presentation

Exclusion Criteria:

- Subject is not a member of vulnerable population

- Subject must not have any disabilities that preclude reliable data collection from the
Actiwatch, e.g., epilepsy with uncontrolled recurring episodes, serious stage
degenerative/disabling disease (e.g. Parkinson's disease), inability to walk or will
require walking aids, etc.